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204881 Complement C3a, Human

Complement C3a, Human, is a native, single chain C3a complement component. It has many biological activities, such as smooth muscle contraction, platelet activation, & immunoregulatory reactions.

Complement C3a, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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204881
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Overview

Replacement Information

Pricing & Availability

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204881-50UG
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      Description
      OverviewNative, human C3a complement component. Single chain, 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzymes (C3 convertases) on target surfaces. The C3 convertase enzymes of either complement activation pathway will cleave the C3 α-chain at peptide bond 77 resulting in the production and release of the C3a peptide. C3a, one of the three complement-derived anaphylatoxins, expresses a wide variety of biological activities which include smooth muscle contraction, platelet and neutrophil activation and aggregation, skin wheal and flare, and immunoregulatory reactions.
      Catalogue Number204881
      Brand Family Calbiochem®
      References
      ReferencesHugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
      Hugli, T.E. 1986. Complement 3, 111.
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2, sterile-filtered through a 0.22 µm filter.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      ContaminantsC3adesArg; ≤10%
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      204881-50UG 04055977219746

      Documentation

      Complement C3a, Human MSDS

      Title

      Safety Data Sheet (SDS) 

      Complement C3a, Human Certificates of Analysis

      TitleLot Number
      204881

      References

      Reference overview
      Hugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
      Hugli, T.E. 1986. Complement 3, 111.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-May-2008 RFH
      DescriptionNative, human C3a complement component. Single chain, 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzyme (C3 convertases) on target surfaces. The C3 convertase enzymes of either complement activation pathway will cleave the C3 α-chain at peptide bond 77, resulting in the production and release of the C3a peptide. C3a, one of the three complement-derived anaphylatoxins, expresses a wide variety of biological activities, which include smooth muscle contraction, platelet and neutrophil activation and aggregation, skin wheal and flare, and immunoregulatory reactions.
      FormLiquid
      FormulationIn PBS, pH 7.2, sterile-filtered through a 0.22 µm filter.
      Concentration Label Please refer to vial label for lot-specific concentration
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥95% by SDS-PAGE
      ContaminantsC3adesArg; ≤10%
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesHugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
      Hugli, T.E. 1986. Complement 3, 111.