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218735 Caspase Inhibitor II - CAS 147837-52-3 - Calbiochem

The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.

Caspase Inhibitor II - CAS 147837-52-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ac-VAD-CHO

Primary Target: pan-caspase
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218735
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
147837-52-3C₁₄H₂₃N₃O₆

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218735-1MG
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      Description
      OverviewA potent and reversible pan-caspase inhibitor.
      Catalogue Number218735
      Brand Family Calbiochem®
      SynonymsAc-VAD-CHO
      References
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Product Information
      CAS number147837-52-3
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₄H₂₃N₃O₆
      Chemical formulaC₁₄H₂₃N₃O₆
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetpan-caspase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Val-Ala-Asp-CHO
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      218735-1MG 04055977218978

      Documentation

      Caspase Inhibitor II - CAS 147837-52-3 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Caspase Inhibitor II - CAS 147837-52-3 - Calbiochem Certificates of Analysis

      TitleLot Number
      218735

      References

      Reference overview
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

      Citations

      Title
    • So-Young Park and Adriana Ferreira. (2005) The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which Tau mediates β-amyloid-induced neurodegeneration. Journal of Neuroscience 25, 5365-5375.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-March-2011 RFH
      SynonymsAc-VAD-CHO
      DescriptionA potent and reversible inhibitor of caspases.
      FormWhite solid
      CAS number147837-52-3
      Chemical formulaC₁₄H₂₃N₃O₆
      Peptide SequenceAc-Val-Ala-Asp-CHO
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (150 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Citation
    • So-Young Park and Adriana Ferreira. (2005) The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which Tau mediates β-amyloid-induced neurodegeneration. Journal of Neuroscience 25, 5365-5375.
      		•