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208735 Calmodulin Inhibitory Peptide - Calbiochem

The Calmodulin Inhibitory Peptide controls the biological activity of Calmodulin. This small molecule/inhibitor is primarily used for Cell Signaling applications.

Calmodulin Inhibitory Peptide - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MLCK Peptide, MLCKP

Primary Target: Calmodulin
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208735
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₉₁H₁₅₆N₃₆O₂₀

Pricing & Availability

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208735-500UG
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      Description
      OverviewA 17-residue peptide based on the calmodulin-binding domain of myosin light chain kinase (MLCK). Binds to calmodulin with high affinity (Kd = 6 pM).
      Catalogue Number208735
      Brand Family Calbiochem®
      SynonymsMLCK Peptide, MLCKP
      References
      ReferencesTorok,K., et al. 1998. Biochemistry 37, 6188.
      Török, K., and Trentham, D.R. 1994. Biochemistry 33, 12807.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₉₁H₁₅₆N₃₆O₂₀
      Chemical formulaC₉₁H₁₅₆N₃₆O₂₀
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCalmodulin
      Primary Target IC<sub>50</sub>Kd = 6 pM in binding to calmodulin
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      208735-500UG 04055977202779

      Documentation

      Calmodulin Inhibitory Peptide - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Calmodulin Inhibitory Peptide - Calbiochem Certificates of Analysis

      TitleLot Number
      208735

      References

      Reference overview
      Torok,K., et al. 1998. Biochemistry 37, 6188.
      Török, K., and Trentham, D.R. 1994. Biochemistry 33, 12807.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-May-2008 RFH
      SynonymsMLCK Peptide, MLCKP
      DescriptionA 17-residue peptide based on the calmodulin-binding domain of myosin light chain kinase (MLCK). Binds to calmodulin with high affinity (Kd = 6 pM). Inhibits calmodulin activation of MLCK-catalyzed phosphorylation of smooth muscle regulatory light chain(MLC).
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₉₁H₁₅₆N₃₆O₂₀
      Peptide SequenceAc-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu-NH₂
      Purity≥95% by HPLC
      SolubilityH₂O (50 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesTorok,K., et al. 1998. Biochemistry 37, 6188.
      Török, K., and Trentham, D.R. 1994. Biochemistry 33, 12807.