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531038 Beclin-1 Activator I, TAT-Beclin-1, Scrambled - Calbiochem

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₆₄H₂₅₁N₅₇O₄₅

Pricing & Availability

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      Description
      OverviewA randomly shuffled Beclin-1 (267-284) peptide made cell-permeable by covalently attaching to HIV-1 Tat protein transduction domain via a diglycine linker. Reported to serve as a suitable control for autophagy-inducing peptides (Cat. nos. 506048 & 506416).

      Please note that the molecular weight for this compound is batch-specific due to variable water content.
      Catalogue Number531038
      Brand Family Calbiochem®
      SynonymsH₂N-YGRKKRRQRRR-GG-VGNDFFINHETTGFATEW-CO₂H
      References
      ReferencesLiu, Y., et al. 2013. Proc. Natl. Acad. Sci. USA 110, 20364.
      Shoji-Kawata, S., et al. 2013. Nature. 494, 201.
      Product Information
      DeclarationSold under license of US Patent 8,722,628.
      FormWhite powder
      FormulationSupplied as trifluoroacetate salt.
      Hill FormulaC₁₆₄H₂₅₁N₅₇O₄₅
      Chemical formulaC₁₆₄H₂₅₁N₅₇O₄₅
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5.31038.0001 04055977242508

      Documentation

      Beclin-1 Activator I, TAT-Beclin-1, Scrambled - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Liu, Y., et al. 2013. Proc. Natl. Acad. Sci. USA 110, 20364.
      Shoji-Kawata, S., et al. 2013. Nature. 494, 201.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-February-2015 JSW
      SynonymsH₂N-YGRKKRRQRRR-GG-VGNDFFINHETTGFATEW-CO₂H
      DescriptionA randomly shuffled Beclin-1 (267-284) peptide made cell-permeable by covalently attaching to HIV-1 Tat protein transduction domain via a diglycine linker. Reported to serve as a suitable control for autophagy-inducing peptides (Cat. nos. 506048 & 506416).
      FormWhite powder
      FormulationSupplied as trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₆₄H₂₅₁N₅₇O₄₅
      Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH
      Purity≥95% by HPLC
      SolubilityH₂O (25 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesLiu, Y., et al. 2013. Proc. Natl. Acad. Sci. USA 110, 20364.
      Shoji-Kawata, S., et al. 2013. Nature. 494, 201.