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203325 BMS - CAS 145626-87-5 - Calbiochem

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203325
  
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      Overview

      Key Spec Table

      CAS #Empirical Formula
      145626-87-5C₄H₁₀O₂S₃
      Description
      OverviewWater-soluble reagent useful for the reduction of native disulfide bonds in proteins. Considered to be a superior reducing agent to DTT. Shown to reduce accessible disulfide bonds in immunoglobulin and trypsinogen under non-denaturing conditions 5 to 7 times faster than DTT at pH 7. The relatively less accessible disulfide bond in α-chymotrypsinogen A was reduced 2.3 times faster at with BMS than with DTT at pH 7.0.
      Catalogue Number203325
      Brand Family Calbiochem®
      Synonymsbis(2-Mercaptoethylsulfone)
      References
      ReferencesSingh, R., et al. 1995. Methods Enzymol. 251, 167.
      Singh, R., and Whitesides, G.M. 1994. Bioorg. Chem. 22, 109.
      Singh, R., and Whitesides, G.M. 1994. Protein Sci. 3, Suppl. 1, 430T.
      Lamoureux, G.V., and Whitesides, G.M. 1993. J. Org. Chem. 58, 633.
      Product Information
      CAS number145626-87-5
      FormWhite crystalline solid
      Hill FormulaC₄H₁₀O₂S₃
      Chemical formulaC₄H₁₀O₂S₃
      PKA7.9 and 9.0
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥99% by titration
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      203325 0