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ABE860 Anti-TRAF3 Antibody

This Anti-TRAF3 Antibody is validated for use in Western Blotting_x000D_ and Immunocytochemistry for the detection of TRAF3.

Anti-TRAF3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Transcription Factors Gene Symbol: TRAF3, CAP1, CRAF1 UniProt Number: Q13114
ABE860
100 μg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE860
      DescriptionAnti-TRAF3 Antibody
      Alternate Names
      • TNF receptor-associated factor 3
      • CAP-1
      • CD40 receptor-associated factor 1
      • CRAF1
      • CD40-binding protein
      • CD40BP
      • LMP1-associated protein 1
      • LAP1
      • TRAF3
      Background InformationTNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationThis Anti-TRAF3 Antibody is validated for use in Western Blotting_x000D_ and Immunocytochemistry for the detection of TRAF3.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis (ICC): 2 μg/mL from a representative lot detected TRAF3 in 3T3 cells.
      Biological Information
      ImmunogenTRAF3 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TRAF3.
      EpitopeNear C-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • TRAF3
      • CAP1
      • CRAF1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~65 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in 3T3 cell lysate.

      Western Blotting Analysis (WB): 1 μg/mL of this antibody detected TRAF3 in 3T3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE860 04055977174649