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07-1473 Anti-Phosphothreonine-Proline Antibody

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07-1473
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number07-1473
      ReplacesAB3192
      DescriptionAnti-Phosphothreonine-Proline Antibody
      Background InformationPhosphothreonine-Proline, along with similar motifs involving serine/threonine residues preceding proline undergoing phosphorylation, has critical roles in the moderation of various cellular processes, protein function, and kinases through proline-directed phosphorylation. The deregulation of proline-directed phosphorylation is known to be a factor in diseases such as cancer and Alzheimer’s neurodegeneration.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Calyculin treated Jurkat cell lysate
      PresentationLiquid in TBS with 0.05% sodium azide and 50% glycerol.
      Quality LevelMQ100
      Applications
      ApplicationDetect Phosphothreonine-Proline using this Anti-Phosphothreonine-Proline Antibody validated for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-phosphothreonine-proline amide
      (pT-P-NH2) peptide conjugates
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes the phosphorylated phothreonine-proline motif, which is the site of phosphorylation of many proline-directed protein kinase such MAPK and cyclin-dependent protein kinases. Also recognizes the phosphoserine-proline motif to a similar degree.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Purification MethodAffinity Purfied
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in Calyculin treated Jurkat cell lysate.
      Western Blot Analysis: 1:500 dilution of this lot detected phosphorylated proteins on 10 μg of calyculin treated Jurkat lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      07-1473 04053252584855

      Documentation

      Anti-Phosphothreonine-Proline Antibody MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Phosphothreonine-Proline Antibody Certificates of Analysis

      TitleLot Number
      Anti- Phosphothreonine-Proline - 2360880 2360880
      Anti- Phosphothreonine-Proline - 2443061 2443061
      Anti- Phosphothreonine-Proline - 2197310 2197310
      Anti- Phosphothreonine-Proline - 3193340 3193340
      Anti- Phosphothreonine-Proline - 3251465 3251465
      Anti- Phosphothreonine-Proline - 3835300 3835300
      Anti- Phosphothreonine-Proline - NRG1704138 NRG1704138
      Anti- Phosphothreonine-Proline -2523900 2523900
      Anti- Phosphothreonine-Proline Polyclonal Antibody 2971921