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AB9610-AF555 Anti-Olig-2 Antibody Alexa Fluor® 555 Conjugate

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AB9610-AF555
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, H, RIFRbAlexaFluor®555Polyclonal Antibody
      Description
      Catalogue NumberAB9610-AF555
      DescriptionAnti-Olig-2 Antibody Alexa Fluor® 555 Conjugate
      Alternate Names
      • Oligodendrocyte transcription factor 2
      • bHLHe19
      • Olg-2
      • Oligo2
      • RACK17
      • RK17
      Background InformationOligodendrocyte transcription factor 2 (UniProt Q9EQW6; also known as bHLHe19, Olg-2, Oligo2, RACK17, RK17) is encoded by the Olig2 (also known as Bhlhb1) gene (Gene ID 50913) in murine species. Olig2 is a basic helix-loop-helix (bHLH) transcription factor expressed in a spinal cord ventricular zone domain where it mediates the sequential generation of motoneurons and oligodendrocytes during embryogenesis. Olig2 also functions as an anti-neurogenic factor in pMN progenitors at early time points to sustain the cycling progenitor pool. The anti-neurogenicity of Olig2 is also responsible for its role in tumorigenesis, especially in brain tumors and leukemia. Due to its expression in glioblastoma and other diffuse gliomas, Olig2 is a useful diagnostic marker of these brain tumors.
      References
      Product Information
      FormatAlexaFluor®555
      PresentationPurified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Olig-2 Antibody Alexa Fluor® 555 Conjugate is an antibody against Olig-2 for use in Immunofluorescence.
      Key Applications
      • Immunofluorescence
      Application NotesThe unconjugated antibody (Cat. No. AB9610) is shown to be suitable also for Western blotting, immunocytochemistry, immunohistochemistry, and immunoprecipitation applications.
      Biological Information
      ImmunogenRecombinant mouse Olig-2.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThe unconjugated antibody (Cat. No. AB9610) recognizes the ~32 kDa Olig-2 protein by Western blotting.
      Species Reactivity
      • Mouse
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Olig2
      • Bhlhb1
      Purification MethodAmmonium Sulfate Precipitation
      UniProt Number
      Molecular Weight~32 kDa observed.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunofluorescence in mouse brain tissue.

      Immunofluorescence Analysis: An 1:150 dilution of this antibody detected Olig-2 in mouse brain tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9610-AF555 04055977329360

      Documentation

      Anti-Olig-2 Antibody Alexa Fluor® 555 Conjugate MSDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Olig-2 Antibody Alexa Fluor® 555 Conjugate Certificates of Analysis

      TitleLot Number
      Anti-Olig-2 Alexa Fluor® 555 -2790877 2790877
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 3167571 3167571
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 3393258 3393258
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 3700365 3700365
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 3776090 3776090
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 3916734 3916734
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 3954355 3954355
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 4050734 4050734
      Anti-Olig-2 Alexa Fluor® 555 Conjugate - 4188105 4188105
      Anti-Olig-2 Alexa Fluor® 555 Conjugate -2781571 2781571

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies