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MABT183 Anti-CLPP, clone 6G7.3

MABT183
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT183
      DescriptionAnti-CLPP, clone 6G7.3
      Alternate Names
      • Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial
      • Endopeptidase ClpP1
      • pClpP
      Background InformationPutative ATP-dependent Clp protease proteolytic subunit, mitochondrial, also known as Endopeptidase Clp, and encoded by the gene name CLPP, belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. CLPP is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. CLPP may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-CLPP Antibody, clone 6G7.3 is an antibody against CLPP for use in Western Blotting and Immunohistochemistry (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CLPP in human liver tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human CLPP.
      Clone6G7.3
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgMκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CLPP
      Purification MethodPurified by Ion-Exchange Chromatography
      UniProt Number
      Molecular Weight~32 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human skeletal muscle tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected CLPP in 200 µg of human skeletal muscle tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABT183 04055977136876