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327768 Angiostatin, Human, Recombinant, Pichia pastoris

Angiostatin, Human, Recombinant, Pichia pastoris MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
327768
  
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      Overview

      Description
      Overview

      This product has been discontinued.

      We apologize for the inconvenience, but we do not currently have an alternative product.






      Recombinant, human angiostatin expressed in Pichia pastoris. Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1-4. A specific inhibitor of endothelial cell proliferation and one of the most potent and specific natural inhibitors of angiogenesis and metastatic tumor growth.
      Catalogue Number327768
      Brand Family Calbiochem®
      References
      ReferencesCao, Y. 1999. Haematologica 84, 643. Sim, B.K., et al. 1997. Cancer Res. 57, 1329. Wu, Z., et al. 1997. Biochem. Biophys. Res. Commun. 236, 651. Cao, Y., et al. 1996. J. Biol. Chem. 271, 29461. O'Reilly, M.S., et al. 1994. Cell 79, 315.
      Product Information
      CAS number86090-08-6
      DeclarationSold under license of U.S. Patents 6,521,439, 6,723,536, and corresponding patents.
      FormLiquid
      FormulationIn 0.9% NaCl.
      Biological Information
      Biological activity10 µg/ml angiostatin will inhibit 60% tube formation in the presence of 10 ng/ml VEGF and 50% tube formation in the presence of 5 ng/ml bFGF.
      Purity≥90% by HPLC
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      ContaminantsEndotoxin: ≤ 0.50 EU/mg
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      327768 0