565773 Sigma-Aldrichγ-Secretase Inhibitor XII - Calbiochem
γ-Secretase Inhibitor XII, is a cell-permeable, reversible inhibitor of γ-secretase activity in vitro (Aβ40 IC50 = 7.9 µM; Aβ42 IC50 = 7.6 µM) and in APP695 expressing CHO 2b-7 cells.
More>> γ-Secretase Inhibitor XII, is a cell-permeable, reversible inhibitor of γ-secretase activity in vitro (Aβ40 IC50 = 7.9 µM; Aβ42 IC50 = 7.6 µM) and in APP695 expressing CHO 2b-7 cells. Less<<Synonyms: Z-IL-CHO
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Overview
Key Spec Table
Empirical Formula |
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C₂₀H₃₀N₂O₄ |
Pricing & Availability
Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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565773-5MG |
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Ampul plastik | 5 mg |
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References | |
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References | Weijzen, S., et al. 2002. Nat. Med. 8, 979. McLendon, C., et al. 2000. FASEB J. 14, 2383. |
Product Information | |
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ATP Competitive | N |
Form | White solid |
Hill Formula | C₂₀H₃₀N₂O₄ |
Chemical formula | C₂₀H₃₀N₂O₄ |
Reversible | Y |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | Aβ40 in vitro |
Primary Target IC<sub>50</sub> | 7.9 µM for Aβ40; 7.6 µM for Aβ42 in vitro |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Peptide Sequence | Z-Ile-Leu-CHO |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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Catalogue Number | GTIN |
565773-5MG | 04055977267860 |