344037 Sigma-AldrichcFMS Receptor Inhibitor II - CAS 959860-85-6 - Calbiochem
The cFMS Receptor Inhibitor II, also referenced under CAS 959860-85-6, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The cFMS Receptor Inhibitor II, also referenced under CAS 959860-85-6, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<cFMS Receptor Inhibitor II - CAS 959860-85-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 4-(3,4-Dimethylanilino)-7-(4-pyridyl)quinoline-3-carboxamide, CSF-1 Receptor Inhibitor II
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Áttekintés
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Kulcsspecifikációk táblázata
| CAS # | Empirical Formula |
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| 959860-85-6 | C₂₃H₂₀N₄O |
| Description | |
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| Overview | A cell-permeable anilinoquinoline compound that acts as a potent, active site-targeting inhibitor of MCSF receptor/cFMS (IC50 = 80 nM). Although equally potent as cFMS Receptor Inhibitor III (Cat. No. 344038) in inhibiting the cFMS-dependent growth of M-NSF-60 cells (IC50 = 0.1 µM), this inhibitor is much more selective against cFMS-independent growth of NSO cells (IC50 >50 µM). |
| Catalogue Number | 344037 |
| Brand Family | Calbiochem® |
| Synonyms | 4-(3,4-Dimethylanilino)-7-(4-pyridyl)quinoline-3-carboxamide, CSF-1 Receptor Inhibitor II |
| References | |
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| References | Smalley, T.L. Jr., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6257. |
| Product Information | |
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| CAS number | 959860-85-6 |
| Form | Yellow solid |
| Hill Formula | C₂₃H₂₀N₄O |
| Chemical formula | C₂₃H₂₀N₄O |
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| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥97% by HPLC |
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| Safety Information | |
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| S Phrase | S: 22-24/25-36/37/39 Do not breathe dust. Avoid contact with skin and eyes. Wear suitable protective clothing, gloves and eye/face protection. |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Katalógusszám | GTIN |
| 344037 | 0 |
Documentation
cFMS Receptor Inhibitor II - CAS 959860-85-6 - Calbiochem MSDS
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cFMS Receptor Inhibitor II - CAS 959860-85-6 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 344037 |
References
| Hivatkozások áttekintése |
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| Smalley, T.L. Jr., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6257. |