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676476 VEGF-C, Rat, Recombinant, S. frugiperda

VEGF-C, Rat, Recombinant, S. frugiperda MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Vascular Endothelial Growth Factor-C

676476
  
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Purity
≥90% by SDS-PAGE
Description
Overview

This product has been discontinued.





Recombinant, rat VEGF-C (129-amino acids lacking the N- and C-terminal extensions and containing only the middle third VEGF homology domain) expressed in S. frugiperda insect cells. Forms primarily non-covalent linked dimers that can phosphorylate VEGF-R3 (Flt-4). Its actions are mediated via VEGFR-2 on vascular endothelial cells. VEGF-C has been shown to be involved in the regulation of growth and differentiation of lymphatic endothelium.
Supplemented with 0.1% BSA or HSA.
Catalogue Number676476
Brand Family Calbiochem®
SynonymsVascular Endothelial Growth Factor-C
References
ReferencesAmioka, T., et al. 2002. Eur. J. Cancer 38, 1413.
Kirkin, V., et al. 2001. Eur. J. Biochem. 268, 5530.
Mandriota, S.J., et al. 2001. EMBO J. 20, 672.
Karkkainen, M.J., and Petrova, T.V. 2000. Oncogene 19, 5598.
Partanen, T.A., et al. 2000. FASEB J. 14, 2087.
Joukov, V., et al. 1997. EMBO J. 16, 3898.
Product Information
FormLyophilized
Applications
Biological Information
Biological activityED₅₀ ≥200 ng/ml as measured by the stimulation of VEGFR-3 phosphorylation in porcine endothelial cells
Purity≥90% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <0.1 ng/µg VEGF-C
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
676476 0

Documentation

VEGF-C, Rat, Recombinant, S. frugiperda MSDS

Title

Safety Data Sheet (SDS) 

VEGF-C, Rat, Recombinant, S. frugiperda Certificates of Analysis

TitleLot Number
676476

References

Hivatkozások áttekintése
Amioka, T., et al. 2002. Eur. J. Cancer 38, 1413.
Kirkin, V., et al. 2001. Eur. J. Biochem. 268, 5530.
Mandriota, S.J., et al. 2001. EMBO J. 20, 672.
Karkkainen, M.J., and Petrova, T.V. 2000. Oncogene 19, 5598.
Partanen, T.A., et al. 2000. FASEB J. 14, 2087.
Joukov, V., et al. 1997. EMBO J. 16, 3898.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-September-2008 RFH
SynonymsVascular Endothelial Growth Factor-C
DescriptionRecombinant, rat VEGF-C (129-amino acids lacking the N- and C-terminal extensions and containing only the middle third VEGF homology domain) expressed in S. frugiperda insect cells. Forms primarily non-covalent linked dimers that can induce phosphorylation of VEGF-R3 (Flt-4). A lymphangiogenic factor that is reported to be involved in the regulation of growth and differentiation of lymphatic endothelium. The rat recombinant VEGF-C includes amino acids 100 (Gly) to 221 (Ile) and additional 7 amino acid linker along with a His•Tag® sequence (6X His). Exhibits approximately 86% homology with human and 97% homology with mouse VEGF-C. The molecular weight ranges from ~18-24 kDa.
FormLyophilized
Purity≥90% by SDS-PAGE
ContaminantsEndotoxin: <0.1 ng/µg VEGF-C
Biological activityED₅₀ ≥200 ng/ml as measured by the stimulation of VEGFR-3 phosphorylation in porcine endothelial cells
SolubilityReconstitute to ≥50 µg/ml in sterile PBS containing ≥0.1% HSA or BSA.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -70°C.
Toxicity Standard Handling
ReferencesAmioka, T., et al. 2002. Eur. J. Cancer 38, 1413.
Kirkin, V., et al. 2001. Eur. J. Biochem. 268, 5530.
Mandriota, S.J., et al. 2001. EMBO J. 20, 672.
Karkkainen, M.J., and Petrova, T.V. 2000. Oncogene 19, 5598.
Partanen, T.A., et al. 2000. FASEB J. 14, 2087.
Joukov, V., et al. 1997. EMBO J. 16, 3898.