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672999 V-ATPase Inhibitor, KM91104 - Calbiochem

672999
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Áttekintés

Kulcsspecifikációk táblázata

Empirical Formula
C₁₄H₁₂N₂O₄

Products

KatalógusszámCsomagolás Menny./csomag
672999-10MG Üvegpalack 10 mg
Description
OverviewA cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC50 of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.
Catalogue Number672999
Brand Family Calbiochem®
SynonymsH+-ATPase Inhibitor
References
ReferencesKartner, N., et al. 2010. J. Biol. Chem. 285, 37476.
Product Information
FormOff-white solid
Hill FormulaC₁₄H₁₂N₂O₄
Chemical formulaC₁₄H₁₂N₂O₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity>98% by HPLC
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Katalógusszám GTIN
672999-10MG 04055977184143