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108219 Trisz(hidroximetil)-aminometán-hidroklorid

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Trisz(hidroximetil)-aminometán-hidroklorid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 1185-53-1 EC Number: 214-684-5 Molar Mass: 157.60 g/mol Chemical Formula: C₄H₁₁NO₃*ClH Hill Formula: C₄H₁₁NO₃˙ ClH
108219
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
1185-53-1214-684-5C₄H₁₁NO₃˙ ClHC₄H₁₁NO₃*ClH157.60 g/mol

Products

KatalógusszámCsomagolás Menny./csomag
1082190003 Kartondoboz 3 x 0,750 kg
1082195000 Muanyagpalack 5 kg
1082199010 Muanyagdob 10 kg
1082199012 Muanyagvödör 12 kg
1082199050 Muanyagdob 50 kg
Description
Catalogue Number108219
SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
DescriptionTris(hydroxymethyl)aminomethane hydrochloride
References
Product Information
CAS number1185-53-1
EC number214-684-5
Hill FormulaC₄H₁₁NO₃˙ ClH
Chemical formulaC₄H₁₁NO₃*ClH
Molar Mass157.60 g/mol
HS Code2922 19 99
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.28 g/cm3 (20.2 °C)
Melting Point150.7 °C
pH value4.2 (100 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (50 °C)
Solubility561 g/l oldható
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Egyéb folyadékok és szilárd anyagok
WGKWGK 1 enyhén vízszennyező
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
Storage+15°C és +25°C között tárolandó.
Packaging Information
Transport Information
Supplemental Information
Specifications
Appearancewhite to almost white, crystalline powder
Assay (alkalimetric, calculated on dried substance)≥ 99.0 %
Identity (IR-spectrum)conforms
pH-value (0.5 mol/l, water)3.5 - 5.0
Melting point147 - 153 °C
UV-Absorption (230 nm; 10 %; 1 cm; water)≤ 0.1
UV-Absorption (260 nm; 10 %, 1 cm; water)≤ 0.06
UV-Absorption (280 nm; 10 %; 1 cm; water)≤ 0.06
UV-Absorption (300 nm; 10 %; 1 cm; water)≤ 0.02
UV-Absorption (400 nm; 10 %; 1 cm; water)≤ 0.01
Residual solvents (ICHQ3C) of class 2 (Methanol)≤ 3000 ppm
Residual solvents (ICHQ3C) of class 2 (Nitromethane)≤ 50 ppm
Residual solvents (ICHQ3C) of class 3 (Ethanol)≤ 5000 ppm
Residual solvents (ICHQ3C) of class 3 (Ethylmethylketon)≤ 5000 ppm
Other residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash≤ 0.03
Loss on Drying (105°C)≤ 0.5
Endotoxins< 2.5
Total aerobic microbial count≤ 10²
Total yeast and mould count
≤ 10²
Salmonella spp.
absent in 10 g
E.coli
absent in 1 g
Staphylococcus aureus
absent in 1 g
Pseudomonas aeruginosa
absent in 1 g
Candida albicans
absent in 1 g
Bile tolerante gram negative bacteria
absent in 1 g
DNases (Exo- and endonucleases)
not detected
Proteases
not detected
RNases
not detected
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Total yeast and mould count
≤ 10²
Salmonella spp.
absent in 10 g
E.coli
absent in 1 g
Staphylococcus aureus
absent in 1 g
Pseudomonas aeruginosa
absent in 1 g
Candida albicans
absent in 1 g
Bile tolerante gram negative bacteria
absent in 1 g
DNases (Exo- and endonucleases)
not detected
Proteases
not detected
RNases
not detected
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Global Trade Item Number
Katalógusszám GTIN
1082190003 04027269296049
1082195000 04022536532899
1082199010 04022536702742
1082199012 04027269285586
1082199050 04054839392443

Documentation

Material Qualification Dossier

TitleVersion
6.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Trisz(hidroximetil)-aminometán-hidroklorid MSDS

Title

Safety Data Sheet (SDS) 

Trisz(hidroximetil)-aminometán-hidroklorid Certificates of Analysis

Cikkszám CsomagolásSpecifikációSarzsszám
1082190003 KartondobozSpecifikációk, PDF dokumentum
1082195000 MuanyagpalackSpecifikációk, PDF dokumentum
1082199010 MuanyagdobSpecifikációk, PDF dokumentum
1082199012 MuanyagvödörSpecifikációk, PDF dokumentum
1082199050 MuanyagdobSpecifikációk, PDF dokumentum

Certificates

Title