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616365 Transdermal Hormone Delivery Peptide, TD-1

616365
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Overview

This product has been discontinued.





A highly hydrophilic [Cys-Cys] cyclic 11-mer peptide that facilitates transdermal protein drug delivery by creating a transient opening in the skin barrier. Topical coadministration of TD-1 has been shown to enable insulin and human growth hormone to reach systemic circulation in rats in vivo.
Catalogue Number616365
Brand Family Calbiochem®
SynonymsH-ACSSSPSKHCG-OH, Cyclic, TD-1
References
ReferencesChen, Y., et al. 2006. Nat. Biotech. 24, 455.
Product Information
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₄₀H₆₄N₁₄O₁₆S₂
Chemical formulaC₄₀H₆₄N₁₄O₁₆S₂
Hygroscopic Hygroscopic
Applications
Biological Information
Purity≥97% by HPLC
Physicochemical Information
Peptide SequenceH₂N-Ala-Cys²-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys¹⁰-Gly-CO₂H (Cyclic 2—>10)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
616365 0

Documentation

Transdermal Hormone Delivery Peptide, TD-1 Certificates of Analysis

TitleLot Number
616365

References

Hivatkozások áttekintése
Chen, Y., et al. 2006. Nat. Biotech. 24, 455.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2008 RFH
SynonymsH-ACSSSPSKHCG-OH, Cyclic, TD-1
DescriptionA highly hydrophilic [Cys-Cys] cyclic 11-mer peptide that facilitates transdermal protein drug delivery by creating a transient opening in the skin barrier. Topical coadministration of TD-1 has been shown to enable insulin and human growth hormone to reach systemic circulation in rats in vivo.
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₄₀H₆₄N₁₄O₁₆S₂
Peptide SequenceH₂N-Ala-Cys²-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys¹⁰-Gly-CO₂H (Cyclic 2—>10)
Purity≥97% by HPLC
SolubilityH₂O (1 mg/ml)
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesChen, Y., et al. 2006. Nat. Biotech. 24, 455.