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574775 Swainsonine, Swainsona canescens - CAS 72741-87-8 - Calbiochem

574775
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Áttekintés

Kulcsspecifikációk táblázata

CAS #Empirical Formula
72741-87-8C₈H₁₅NO₃

Products

KatalógusszámCsomagolás Menny./csomag
574775-500UG Muanyagampulla 500 μg
Description
OverviewReversible active-site inhibitor of lysosomal α-mannosidase. Inhibits the growth of tumors and prevents metastasis in murine models. Blocks the processing of high mannose to complex type oligosaccharides.
Catalogue Number574775
Brand Family Calbiochem®
Synonyms(1S,2S,8R,8aR)-Trihydroxyindolizidine, 8aβ-Indolizidine-1α,2α,8β-triol
References
ReferencesMochizuki, H., et al. 1993. J. Biol. Chem. 268, 9143.
Elbein, A.D. 1983. Methods Enzymol. 98, 135.
Product Information
CAS number72741-87-8
ATP CompetitiveN
FormWhite solid
Hill FormulaC₈H₁₅NO₃
Chemical formulaC₈H₁₅NO₃
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetLysosomal α-mannosidase
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Global Trade Item Number
Katalógusszám GTIN
574775-500UG 04055977189711