Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

572201 Streptozotocin - CAS 18883-66-4 - Calbiochem

An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.

Streptozotocin - CAS 18883-66-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose

572201
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
18883-66-4C₈H₁₅N₃O₇
Description
OverviewAn N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.
Catalogue Number572201
Brand Family Calbiochem®
Synonyms2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
References
ReferencesKroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
Kwon, N.S., et al. 1994. FASEB J. 8, 529.
Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
Yamamoto, H., et al. 1981. Nature 294, 284.
Product Information
CAS number18883-66-4
FormOff-white to pale yellow crystalline solid
Hill FormulaC₈H₁₅N₃O₇
Chemical formulaC₈H₁₅N₃O₇
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
ContaminantsHeavy metals: ≤5 ppm
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSLZ5775000
Safety Information
R PhraseR: 20/21/22-45-46-61

Harmful by inhalation, in contact with skin and if swallowed.
May cause cancer.
May cause heritable genetic damage.
May cause harm to the unborn child.
S PhraseS: 22-36/37/39-45

Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
572201 0

Documentation

Streptozotocin - CAS 18883-66-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Streptozotocin - CAS 18883-66-4 - Calbiochem Certificates of Analysis

TitleLot Number
572201

References

Hivatkozások áttekintése
Kroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
Kwon, N.S., et al. 1994. FASEB J. 8, 529.
Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
Yamamoto, H., et al. 1981. Nature 294, 284.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision24-September-2010 JSW
Synonyms2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
DescriptionAn N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells. A diabetogenic agent.
FormOff-white to pale yellow crystalline solid
CAS number18883-66-4
RTECSLZ5775000
Chemical formulaC₈H₁₅N₃O₇
Structure formulaStructure formula
Purity≥95% by HPLC
ContaminantsHeavy metals: ≤5 ppm
SolubilityH₂O
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).
Toxicity Harmful & Carcinogenic / Teratogenic
Merck USA index14, 8832
ReferencesKroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler 376, 179.
Kwon, N.S., et al. 1994. FASEB J. 8, 529.
Rasschaert, J., et al. 1992. Endocrinology 130, 3522.
Bennett, R.A. and Pegg, A.E. 1981. Cancer Res. 41, 2786.
Yamamoto, H., et al. 1981. Nature 294, 284.