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14-929M STK25, active

STK25, active MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-929M
250 µg  Also available in 10μg size as catalog # 14-929 and in bulk as catalog # 14-929-K.
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Catalogue Number14-929M
Trade Name
  • Upstate
DescriptionSTK25, active
OverviewSTK25 is a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18.
References
Product Information
Presentation50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
Quality LevelMQ100
Applications
Key Applications
  • Kinase Assay
Biological Information
SourceN-terminal GST-tagged and C-terminal 6His-tagged, recombinant, human STK25 amino acids 1-308, expressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • STK25
  • SOK1
  • YSK1
  • SOK-1
Purification MethodPurified using glutathione sepharose.
Target Sub-FamilySTE
UniProt Number
Molecular Weight63 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of RLGRDKYKTLRQIRQ
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10μg size as catalog # 14-929 and in bulk as catalog # 14-929-K.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
14-929M 04053252922374

Kapcsolódó termékek és alkalmazások

Alternative Packsize

Katalógusszám Leírás
14-929 STK25, active

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Kategóriák

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases