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20-122 S6 Kinase Substrate Cocktail

S6 Kinase Substrate Cocktail MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Kinase Assay
20-122
1 mL  
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Key Applications
KA
Description
Catalogue Number20-122
Brand Family Upstate
Trade Name
  • Upstate
DescriptionS6 Kinase Substrate Cocktail
References
Product Information
Presentation20mM MOPS, pH 7.2, 25mM β-glycerophosphate, 5mM EGTA, 1mM sodium orthovanadate, 1mM dithiothreitol.
Quality LevelMQ100
Applications
Key Applications
  • Kinase Assay
Application NotesFor use in kinase assays.
Biological Information
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Gene Symbol
  • RPS6KA1
  • pp90RSK1
  • HU-1
  • RSK-1
  • MAPKAPK1A
  • p90S6K
  • RSK1
  • RSK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9UK32 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
COFACTOR: Magnesium (By similarity).
SIZE: 745 amino acids; 83872 Da
SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity).
PTM: Autophosphorylated on Ser-389, as part of the activation process (By similarity).
SIMILARITY: SwissProt: Q9UK32 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions1 year at -20°C
Packaging Information
Material Size1 mL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
20-122 04053252326677