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504637 (S)-MCPG - CAS 150145-89-4 - Calbiochem

(S)-MCPG - CAS 150145-89-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (S)-α-Methyl-4-carboxyphenylglycine, Group I/II mGlu Antagonist, (S)-MCPG

Primary Target: Grup I and II mGlu receptors
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
150145-89-4C₁₀H₁₁NO₄
Description
Overview

This product has been discontinued.



A non-selective antagonist for group I/II mGlu receptors (minimal values of IC50 reported = 40 and 15 µM for mGlu1 and mGlu2, respectively). Often used as an agent to differentiate excitatory neurotransmissions mediated by glutamate from other neurotransmitters (i.e. dopamine, acetylcholine, and GABA in early brain development). A common component of cocktails for blocking glutamate transmission in brain slice preparation.
Catalogue Number504637
Brand Family Calbiochem®
Synonyms(S)-α-Methyl-4-carboxyphenylglycine, Group I/II mGlu Antagonist, (S)-MCPG
References
ReferencesFano, S., et al. 2012. Eur. J. Neurosci. 36, 3628.
Wang, W., et al. 2012. J. Physiol. 590, 3743.
Cortes, C., et al. 2013. Synapse. DOI: 10.1002/syn.21646. Schoepp, D.D., et al. 1999.
Neuropharmacol. 38, 1431.
Product Information
CAS number150145-89-4
FormWhite solid
Hill FormulaC₁₀H₁₁NO₄
Chemical formulaC₁₀H₁₁NO₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetGrup I and II mGlu receptors
Primary Target IC<sub>50</sub>40 and 15 →M for mGlu₁ and mGlu₂, respectively.
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
504637 0

Documentation

(S)-MCPG - CAS 150145-89-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Hivatkozások áttekintése
Fano, S., et al. 2012. Eur. J. Neurosci. 36, 3628.
Wang, W., et al. 2012. J. Physiol. 590, 3743.
Cortes, C., et al. 2013. Synapse. DOI: 10.1002/syn.21646. Schoepp, D.D., et al. 1999.
Neuropharmacol. 38, 1431.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-June-2013 JSW
Synonyms(S)-α-Methyl-4-carboxyphenylglycine, Group I/II mGlu Antagonist, (S)-MCPG
DescriptionA non-selective antagonist for group I/II mGlu receptors (minimal values of IC50 reported = 40 and 15 µM for mGlu1 and mGlu2, respectively). Often used as an agent to differentiate excitatory neurotransmissions mediated by glutamate from other neurotransmitters (i.e. dopamine, acetylcholine, and GABA in early brain development). A common component of cocktails for blocking glutamate transmission in brain slice preparation.
FormWhite solid
CAS number150145-89-4
Chemical formulaC₁₀H₁₁NO₄
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityH₂O (10 mM) or DMSO (10 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesFano, S., et al. 2012. Eur. J. Neurosci. 36, 3628.
Wang, W., et al. 2012. J. Physiol. 590, 3743.
Cortes, C., et al. 2013. Synapse. DOI: 10.1002/syn.21646. Schoepp, D.D., et al. 1999.
Neuropharmacol. 38, 1431.