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539183 Proteasome Inhibitor VIII, β-Lactam 3 - CAS 870528-53-3 - Calbiochem

Proteasome Inhibitor VIII, β-Lactam 3 - CAS 870528-53-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: β-Lactam 3

Primary Target: 20S proteasome
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
870528-53-3C₁₁H₁₇ClN₂O₃
Description
Overview

This product has been discontinued.



A β-lactam analog of Proteasome Inhibitor VII, Antiprotealide (Cat. No. 539179) that acts as a selective and irreversible inhibitor of the 20S proteasome. While the rate of proteasome inhibition is slower than Omuralide (Cat. No. 426102), β-lactam 3 displays prolonged aqueous stability and therefore may be better suited for biological evaluation.
Catalogue Number539183
Brand Family Calbiochem®
Synonymsβ-Lactam 3
References
ReferencesHogan, P.C. and Corey, E.J. 2005. J. Am. Chem. Soc. 127, 15386.
Product Information
CAS number870528-53-3
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₁H₁₇ClN₂O₃
Chemical formulaC₁₁H₁₇ClN₂O₃
ReversibleN
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary Target20S proteasome
Purity≥95% by NMR
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
539183 0

Documentation

Proteasome Inhibitor VIII, β-Lactam 3 - CAS 870528-53-3 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Proteasome Inhibitor VIII, β-Lactam 3 - CAS 870528-53-3 - Calbiochem Certificates of Analysis

TitleLot Number
539183

References

Hivatkozások áttekintése
Hogan, P.C. and Corey, E.J. 2005. J. Am. Chem. Soc. 127, 15386.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-April-2011 RFH
Synonymsβ-Lactam 3
DescriptionA β-lactam analog of Proteasome Inhibitor VII, Antiprotealide (Cat. No. 539179) that acts as a selective and irreversible inhibitor of the 20S proteasome. While the rate of proteasome inhibition is slower than Omuralide (Cat. No. 426102), β-lactam 3 displays prolonged aqueous stability and therefore may be better suited for biological evaluation.
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number870528-53-3
Chemical formulaC₁₁H₁₇ClN₂O₃
Structure formulaStructure formula
Purity≥95% by NMR
SolubilityDMSO (10 mg/ml)
Storage Protect from moisture
Protect from light
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
Toxicity Standard Handling
ReferencesHogan, P.C. and Corey, E.J. 2005. J. Am. Chem. Soc. 127, 15386.