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512731 Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity.

Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Neomycin E

512731
  
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
1263-89-4C₂₃H₄₅N₅O₁₄ · H₂SO₄
Description
OverviewAn aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates that paromomycin binding to the A-site of 16S rRNA induces a local conformational change, suggesting a mechanism for aminoglycoside action on protein translation. Also exhibits anti-protozoal properties.
Potency: ≥675 µg/mg.
Catalogue Number512731
Brand Family Calbiochem®
SynonymsNeomycin E
References
ReferencesVanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.
Product Information
CAS number1263-89-4
FormOff-white solid
Hill FormulaC₂₃H₄₅N₅O₁₄ · H₂SO₄
Chemical formulaC₂₃H₄₅N₅O₁₄ · H₂SO₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSWK2320000
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 22-24/25-36/37/39-45

Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
512731 0

Documentation

Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem Certificates of Analysis

TitleLot Number
512731

References

Hivatkozások áttekintése
VanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-October-2010 JSW
SynonymsNeomycin E
DescriptionAn aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates paromomycin binding to the A-site of 16S rRNA induces a local conformational change that suggests a mechanism for aminoglycoside action on protein translation.
FormOff-white solid
CAS number1263-89-4
RTECSWK2320000
Chemical formulaC₂₃H₄₅N₅O₁₄ · H₂SO₄
Structure formulaStructure formula
SolubilityH₂O
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Toxicity Harmful
Merck USA index14, 7041
ReferencesVanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.