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482675 Nitric Oxide Donor Set

482675
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Overview

This product has been discontinued.





Contains 20 mg of (±)-S-Nitroso-N-acetylpenicillamine (SNAP; Cat. No. 487910), 10 mg of NOR-3 (Cat. No. 489530), 10 mg of 4-Phenyl-3-furoxancarbonitrile, 20 mg of SIN-1, Hydrochloride (Cat. No. 567028), and 100 mg of Sodium Nitroprusside (Cat. No. 567538). Supplied with a data sheet.
Catalogue Number482675
Brand Family Calbiochem®
References
ReferencesWink, D.A., et al. 1996. Arch. Biochem. Biophys. 331, 241.
Asahi, M., et al. 1995. J. Biol. Chem. 270, 21035.
Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
Ferioli, R., et al. 1995. Br. J. Pharmacol. 114, 816.
Kita, Y., et al. 1994. Eur. J. Pharmacol. 257, 123.
Kowaluk, E.A., et al. 1992. J. Pharmacol. Exp. Ther. 262, 916.
Feelisch, M., et al. 1989. J. Cardiovasc. Pharmacol. 14, S13.
Hino, N., et al. 1989. J. Antibiot. 42, 1578.
Product Information
FormSolid
Hygroscopic Hygroscopic
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 26/27/28-36/37/38

Very toxic by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
S PhraseS: 22-36/37/39-45-26

Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Multiple Toxicity Values, refer to MSDS
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsSIN-1, NOR-3, SNAP, and 4-Phenyl-3-furoxancarbonitrile are not stable in solution and should be reconstituted just prior to use. Stock solutions of sodium nitroprusside for up to 2 weeks at 4°C in the dark. NOR-3, 4-Phenyl-3-furoxancarbonitrile, sodium nitroprusside, and SNAP should be protected from light.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
482675 0

Documentation

Nitric Oxide Donor Set Certificates of Analysis

TitleLot Number
482675

References

Hivatkozások áttekintése
Wink, D.A., et al. 1996. Arch. Biochem. Biophys. 331, 241.
Asahi, M., et al. 1995. J. Biol. Chem. 270, 21035.
Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
Ferioli, R., et al. 1995. Br. J. Pharmacol. 114, 816.
Kita, Y., et al. 1994. Eur. J. Pharmacol. 257, 123.
Kowaluk, E.A., et al. 1992. J. Pharmacol. Exp. Ther. 262, 916.
Feelisch, M., et al. 1989. J. Cardiovasc. Pharmacol. 14, S13.
Hino, N., et al. 1989. J. Antibiot. 42, 1578.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-August-2008JSW
DescriptionNitric oxide (NO) is an intracellular messenger molecule with multiple regulatory functions, including neurotransmission, control of blood pressure, platelet aggregation, smooth muscle relaxation, and macrophage-mediated cytotoxicity. Calbiochem® offers a wide variety of NO donors for the study of these intracellular pathways. Now we have packaged several of our most popular NO donors into one convenient set. The table below lists the biological properties of these compounds. Supplied with a data sheet.
FormSolid
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsSIN-1, NOR-3, SNAP, and 4-Phenyl-3-furoxancarbonitrile are not stable in solution and should be reconstituted just prior to use. Stock solutions of sodium nitroprusside for up to 2 weeks at 4°C in the dark. NOR-3, 4-Phenyl-3-furoxancarbonitrile, sodium nitroprusside, and SNAP should be protected from light.
Toxicity Multiple Toxicity Values, refer to MSDS
ReferencesWink, D.A., et al. 1996. Arch. Biochem. Biophys. 331, 241.
Asahi, M., et al. 1995. J. Biol. Chem. 270, 21035.
Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1.
Ferioli, R., et al. 1995. Br. J. Pharmacol. 114, 816.
Kita, Y., et al. 1994. Eur. J. Pharmacol. 257, 123.
Kowaluk, E.A., et al. 1992. J. Pharmacol. Exp. Ther. 262, 916.
Feelisch, M., et al. 1989. J. Cardiovasc. Pharmacol. 14, S13.
Hino, N., et al. 1989. J. Antibiot. 42, 1578.