Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

AG345 Na+/H+ Exchanger-1, Control Peptide for AB3081/AB3082

Na+/H+ Exchanger-1, Control Peptide for AB3081/AB3082 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Gene Symbol: SLC9A1, FLJ42224, APNH, NHE-1, Na, +H, NHE1, APNH1 UniProt Number: P19634
AG345
100 µg  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Catalogue NumberAG345
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionNa+/H+ Exchanger-1, Control Peptide for AB3081/AB3082
OverviewNa+/H+ Exchanger 1 (NHE1) control peptide.
References
Product Information
PresentationLiquid in PBS, pH 7.5.
Quality LevelMQ100
Applications
Key Applications
  • Peptide Inhibition Assay
Application NotesAntibody blocking (AB3081/AB3082)

Optimal working concentration must be determined by the end user.
Biological Information
Concentration1 mg/mL
Entrez Gene Number
Gene Symbol
  • SLC9A1
  • FLJ42224
  • APNH
  • NHE-1
  • Na
  • +H
  • NHE1
  • APNH1
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P19634 # Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
SIZE: 815 amino acids; 90763 Da
SUBUNIT: Interacts with tescalcin, CHP and CHP2.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Kidney and intestine.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. & O-glycosylated.
SIMILARITY: SwissProt: P19634 ## Belongs to the Na(+)/H(+) exchanger (TC 2.A.36.5.1) family.
MISCELLANEOUS: Inhibited by amiloride and 5-amino-substituted derivatives and activated in a cooperative fashion by intracellular H(+). In quiescent cells upon growth factor stimulation, the apparent affinity for internal H(+) is increased, resulting in a persistent rise in cytoplasmic pH.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
AG345 04053252364952

Documentation

Na+/H+ Exchanger-1, Control Peptide for AB3081/AB3082 MSDS

Title

Safety Data Sheet (SDS) 

Na+/H+ Exchanger-1, Control Peptide for AB3081/AB3082 Certificates of Analysis

TitleLot Number
Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE - 1999456 1999456
Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE - 2005381 2005381
Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE - 2037598 2037598

References

Reference overviewPub Med ID
Identification of the Na+/H+ exchanger 1 in dorsal root ganglion and spinal cord: its possible role in inflammatory nociception.
H I Rocha-González,G Castañeda-Corral,C I Araiza-Saldaña,M Ambriz-Tututi,N L Caram-Salas,J E Torres-López,J Murbartián,V Granados-Soto
Neuroscience  160  2009

Kivonat megmutatása 		19248819 19248819

Data Sheet

Title
Na+/H+ EXCHANGER 1 (NHE1) CONTROL PEPTIDE