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504528 NVP-AAM077 Tetrasodium Hydrate - CAS 459836-30-7 - Calbiochem

NVP-AAM077 Tetrasodium Hydrate - CAS 459836-30-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NVP-AAM077, [[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium hydrate, PEAQX tetrasodium hydrate, NMDA Antagonist VII

Primary Target: NMDA receptors
504528
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
459836-30-7C₁₇H₁₇BrN₃Na₄O₆P

Products

KatalógusszámCsomagolás Menny./csomag
5.04528.0001 Üvegpalack 5 mg
Description
OverviewA potent antagonist for NMDA receptors. Modestly higher selectivity for the NR2A than for the NR2B containing NMDA receptors (IC50 = 0.015 and 0.078 µM) but insufficient to discriminate between NR2A and NR2B-containing NMDA receptors. Widely used for researches in synaptic plastic, learning and memory, and epilepsy.
Catalogue Number504528
Brand Family Calbiochem®
SynonymsNVP-AAM077, [[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium hydrate, PEAQX tetrasodium hydrate, NMDA Antagonist VII
References
ReferencesFrizelle. P., et al. 2006. Mol. Pharmacol. 70, 1022.
Milton, A., et al. 2013. J. Neurosci. 33, 1109.
Kochlamazashvili, G., et al. 2012. J. Neurosci. 32, 2263.
Kocsis, B., et al. 2012. Sleep. 35, 1011.
Product Information
CAS number459836-30-7
FormWhite solid
Hill FormulaC₁₇H₁₇BrN₃Na₄O₆P
Chemical formulaC₁₇H₁₇BrN₃Na₄O₆P
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNMDA receptors
Primary Target IC<sub>50</sub>0.015 and 0.078 µM for NR2A and NR2B, respectively.
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
5.04528.0001 04055977263756

Documentation

NVP-AAM077 Tetrasodium Hydrate - CAS 459836-30-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

NVP-AAM077 Tetrasodium Hydrate - CAS 459836-30-7 - Calbiochem Certificates of Analysis

TitleLot Number
504528

References

Hivatkozások áttekintése
Frizelle. P., et al. 2006. Mol. Pharmacol. 70, 1022.
Milton, A., et al. 2013. J. Neurosci. 33, 1109.
Kochlamazashvili, G., et al. 2012. J. Neurosci. 32, 2263.
Kocsis, B., et al. 2012. Sleep. 35, 1011.

Brochure

Title
Pathways and Biomarkers of Glutamatergic Synapse Flyer
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-March-2015 JSW
SynonymsNVP-AAM077, [[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium hydrate, PEAQX tetrasodium hydrate, NMDA Antagonist VII
DescriptionA potent antagonist for NMDA receptors. Modestly higher selectivity for the NR2A than for the NR2B containing NMDA receptors (IC50 = 0.015 and 0.078 µM) but insufficient to discriminate between NR2A and NR2B-containing NMDA receptors. Widely used for researches in synaptic plastic, learning and memory, and epilepsy.
FormWhite solid
CAS number459836-30-7
Chemical formulaC₁₇H₁₇BrN₃Na₄O₆P
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityH₂O (24 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesFrizelle. P., et al. 2006. Mol. Pharmacol. 70, 1022.
Milton, A., et al. 2013. J. Neurosci. 33, 1109.
Kochlamazashvili, G., et al. 2012. J. Neurosci. 32, 2263.
Kocsis, B., et al. 2012. Sleep. 35, 1011.