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TGFBMAG-64K-01BK MILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit Space Saver (Bulk) Packaging

This MILLIPLEX MAP TGF ß1 (Transforming Growth Factor Beta) - Single Plex is an Immunology Multiplex Assay used for the simultaneous quantification of theTGF-β1 biomarker in the following species: Mouse/Human/Rat/Pig/Horse/Rabbit/Guinea Pig/Hamster.

MILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit Space Saver (Bulk) Packaging MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Inflammation & Immunology
TGFBMAG-64K-01BK
96-well plate  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
TGF-β1 H, M, R, NhP, Ca, Fe, PoMplexLuminex xMAP
Description
Catalogue NumberTGFBMAG-64K-01BK
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit Space Saver (Bulk) Packaging
Background InformationThe transforming growth factor beta (TGFβ) system, a superfamily of cytokines as well as signaling pathways, is highly conserved throughout the animal kingdom. TGFβ functions in immune cell development, angiogenesis, wound healing and embryonic development, bone development and plays a critical role in immune response, heart disease, and cancer. In its normal state TGFβ is one of the few classes of proteins able to inhibit cell growth by halting mitosis at the G1 state, inducing cell differentiation or apoptosis. However, during oncogenesis mutations in the TGFβ signaling pathway result in tumor cell resistance to the effects of normally functioning TGFβ, causing proliferation without regulation. Initial research suggests that VE-cadherin may enhance the mutated TGFβ signaling pathway.
References
Product Information
Detection methodLuminex xMAP
HS Code3822 19 90
ConfigurationSingle Plex
Precision, %
  • Inter-assay: < 10
  • Intra-assay: < 10
Panel TypeMAGNETIC Cytokines/Chemokines
Quality LevelMQ200
Applications
ApplicationThis MILLIPLEX MAP TGF ß1 (Transforming Growth Factor Beta) - Single Plex is an Immunology Multiplex Assay used for the simultaneous quantification of theTGF-β1 biomarker in the following species: Mouse/Human/Rat/Pig/Horse/Rabbit/Guinea Pig/Hamster.
Key Applications
  • Multiplexing
Application Notes• This assay requires an acidification sample treatment.
• This is a 2-hour or overnight incubation assay.
• This assay requires 25 μL of a 1:30 dilution after treatment of serum and plasma samples.
Biological Information
SpecificityIn addition to human TGFβ1, the assay can detect TGFβ1 in serum of the following; horse, rabbit, mouse, rat, mini pig, canine, hamster, guinea pig, rhesus monkey and cynomolgous monkey. However, the exact amount of cross reactivity has not been determined.
Species Reactivity
  • Human
  • Mouse
  • Rat
  • Non-human Primate
  • Canine
  • Feline
  • Pig
Analytes Available
  • TGF-β1
Physicochemical Information
Sensitivity
  • 12 pg/mL
Standard Curve Range
  • 9.8 - 2,500 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
TGFBMAG-64K-01BK 04055977114317