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14-510M Lyn Protein, active, 250 µg

14-510M
250 µg  Also available in 10 μg size (cat#14-510) and in bulk (cat# 14-510-K).
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Catalogue Number14-510M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionLyn Protein, active, 250 µg
OverviewN-terminal his6-tagged recombinant full-length human Lyn
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal his6-tagged recombinant full-length human Lyn, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Application NotesKinase Assays: Depending upon the specific activity of the lot , 7.6 -15.3ng of enzyme phosphorylated 0.1 mg/ml poly (Glu, Tyr) 4:1 {Sigma P7244} in a standard kinase assay. See technical datasheet included with purchased product for lot specific activity values.
Biological Information
Sourceexpressed in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • LYN
  • JTK8
  • FLJ26625
Protein TargetLyn
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummarySIZE: 512 amino acids; 58574 Da
SUBUNIT: Interacts with phosphorylated LIME1 and with CD79A upon BCR activation. Interacts with Epstein-Barr virus LMP2A. Interacts with TGFB1I1.
TISSUE SPECIFICITY: Expressed in primary neuroblastoma tumors.
SIMILARITY: SwissProt: P07948 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Molecular Weight59.6kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-510) and in bulk (cat# 14-510-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
14-510M 04053252270796

Kapcsolódó termékek és alkalmazások

Alternative Packsize

Katalógusszám Leírás
14-510 Lyn Protein, active, 10 µg

Product Families

Kategóriák

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases