435800 Sigma-AldrichLicochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem
Licochalcone-A, Synthetic, CAS 58749-22-7, is an estrogenic flavonoid with anti-tumor & antiparasitic properties. Reduces Bcl-2 expression and induces apoptosis in several human cancer cell lines.
More>> Licochalcone-A, Synthetic, CAS 58749-22-7, is an estrogenic flavonoid with anti-tumor & antiparasitic properties. Reduces Bcl-2 expression and induces apoptosis in several human cancer cell lines. Less<<Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one
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Áttekintés
| Replacement Information |
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Kulcsspecifikációk táblázata
| CAS # | Empirical Formula |
|---|---|
| 58749-22-7 | C₂₁H₂₂O₄ |
Products
| Katalógusszám | Csomagolás | Menny./csomag | |
|---|---|---|---|
| 435800-10MG | Muanyagampulla | 10 mg | |
| 435800-50MG | Muanyagampulla | 50 mg |
| Description | |
|---|---|
| Overview | An estrogenic flavonoid with anti-tumor and antiparasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation, exhibits anti-tumor activity, and enhances the effect of Paclitaxel (Cat. No. 580555) and Vinblastine (Cat. No. 677175) chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism. |
| Catalogue Number | 435800 |
| Brand Family | Calbiochem® |
| Synonyms | (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one |
| Product Information | |
|---|---|
| CAS number | 58749-22-7 |
| ATP Competitive | N |
| Form | Yellow solid |
| Hill Formula | C₂₁H₂₂O₄ |
| Chemical formula | C₂₁H₂₂O₄ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | Anti-tumor and antiparasitic properties |
| Purity | ≥96% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information | |
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| R Phrase | R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
| S Phrase | S: 36 Wear suitable protective clothing. |
| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
|---|---|
| Katalógusszám | GTIN |
| 435800-10MG | 04055977210309 |
| 435800-50MG | 04055977210316 |
Documentation
Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem MSDS
| Title |
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Licochalcone-A, Synthetic - CAS 58749-22-7 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 435800 |
References
| Hivatkozások áttekintése |
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| Rafi, M.M., et al. 2000. Anticancer Res. 20, 2653. Zhai, L., et al. 1999. J. Antimicrob. Chemother. 43, 793. Haraguchi, H., et al. 1998. Phytochemistry 48, 125. Park, E.J., et al. 1998. Planta Med. 64, 464. Chen, M., et al. 1994. Antimicrob. Agents Chemother. 38, 1470. Chen, M., et al. 1993. Antimicrob. Agents. Chemother. 37, 2550. |
Brochure
| Title |
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| Caspases and other Apoptosis Related Tools Brochure |