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437600 LPD-12

LPD-12 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Lipopeptide Detergent-12, Ac-AO(C₁₂)AEAAEKAAKYAAEAAEKAAKAO(C₁₂)A-NH₂

437600
  
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Empirical Formula
C₁₃₁H₂₂₄N₃₂O₃₇
Description
Overview

This product has been discontinued.



A water soluble, amphiphilic α-helical lipopeptide detergent (LPD) that forms small micelles and effectively mimics lipid bilayers (solubility in PBS ~ 40 mM; micelle MW ~ 23,100; aggregation number ~ 8.1; partial specific volume ~ 0.77 cm3/g). Shown to not only solubilize but also stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~ 250 µM and [protein] ~ 22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins.
Catalogue Number437600
Brand Family Calbiochem®
SynonymsLipopeptide Detergent-12, Ac-AO(C₁₂)AEAAEKAAKYAAEAAEKAAKAO(C₁₂)A-NH₂
References
ReferencesMcGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171.
Product Information
CMC< 1 μM
FormWhite lyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₃₁H₂₂₄N₃₂O₃₇
Chemical formulaC₁₃₁H₂₂₄N₃₂O₃₇
Hygroscopic Hygroscopic
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Peptide SequenceAc-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
437600 0

Documentation

LPD-12 MSDS

Title

Safety Data Sheet (SDS) 

LPD-12 Certificates of Analysis

TitleLot Number
437600

References

Hivatkozások áttekintése
McGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171.

Brochure

Title
Biological Detergents Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-August-2008 RFH
SynonymsLipopeptide Detergent-12, Ac-AO(C₁₂)AEAAEKAAKYAAEAAEKAAKAO(C₁₂)A-NH₂
DescriptionA water soluble, amphiphilic α-helical, non-denaturing lipopeptide detergent (LPD) that forms small micelles (CMC <1 µM; micelle MW ~23,100; aggregation number ~8.1; partial specific volume ~0.77 cm3/g) and effectively mimics lipid bilayers. Shown to solubilize as well as stabilize bacteriorhodopsin, lactose permease and E. coli PagP protein ([LPD] ~250 µM and [protein] ~22 µM) by forming complexes and precluding aggregation. Useful for NMR and X-ray structural studies of membrane proteins.
FormWhite lyophilized
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₁₃₁H₂₂₄N₃₂O₃₇
Peptide SequenceAc-Ala-Orn(dodecanoyl)-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Tyr-Ala-Ala-Glu-Ala-Ala-Glu-Lys-Ala-Ala-Lys-Ala-Orn(dodecanoyl)-Ala-NH₂
Purity≥95% by HPLC
SolubilityH₂O (100 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Irritant
ReferencesMcGregor, C.L., et al. 2003. Nat. Biotechnol. 21, 171.