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420106 JAK3 Inhibitor III

JAK3 Inhibitor III MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-(3ʹ,5ʹ-Dibromo-4-hydroxyphenyl)amino-6,7-dimethoxyquinazoline, WHI-P97

420106
  
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Áttekintés

Replacement Information
Description
Overview

This product has been discontinued.

Please refer to our complete listing of JAK3 inhibitors for possible alternatives. Please read all alternative product documentation carefully and contact technical service if you need additional information.





A potent cell-permeable and specific inhibitor of JAK3 (IC50 = 11 µM). Inhibits JAK3 in immune complex kinase assays in a dose-dependent fashion and reduces the invasiveness of EGFR positive human cancer cells in a dose-dependent manner.
Catalogue Number420106
Brand Family Calbiochem®
Synonyms4-(3ʹ,5ʹ-Dibromo-4-hydroxyphenyl)amino-6,7-dimethoxyquinazoline, WHI-P97
References
ReferencesGhosh, S., et al. 1999. Anticancer Res. 14, 403. Sudbeck, E.A., et al. 1999 Clin. Cancer Res. 5, 1569.
Product Information
CAS number211555-05-4
FormPale yellow solid
Hill FormulaC₁₆H₁₃Br₂N₃O₃
Chemical formulaC₁₆H₁₃Br₂N₃O₃
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetJAK-3
Primary Target IC<sub>50</sub>11 µM
Purity≥92% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
420106 0

Documentation

JAK3 Inhibitor III Certificates of Analysis

TitleLot Number
420106

References

Hivatkozások áttekintése
Ghosh, S., et al. 1999. Anticancer Res. 14, 403. Sudbeck, E.A., et al. 1999 Clin. Cancer Res. 5, 1569.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-September-2007 JSW
Synonyms4-(3ʹ,5ʹ-Dibromo-4-hydroxyphenyl)amino-6,7-dimethoxyquinazoline, WHI-P97
DescriptionA potent and specific inhibitor of JAK3 (IC50 = 11 µM). Inhibits JAK3 in immune complex kinase assays in a dose-dependent fashion.
FormPale yellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number211555-05-4
Chemical formulaC₁₆H₁₃Br₂N₃O₃
Structure formulaStructure formula
Purity≥92% by HPLC
SolubilityDMSO (5 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesGhosh, S., et al. 1999. Anticancer Res. 14, 403. Sudbeck, E.A., et al. 1999 Clin. Cancer Res. 5, 1569.