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371956 Iso-H-7, Dihydrochloride

371956
  
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Áttekintés

Replacement Information
Description
Overview

This product has been discontinued.

We are currently only offering the parent inhibitor, H-7, Dihydrochloride (Cat. No. 371955) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.





Cell permable and less potent than H-7 in inhibiting rat brain protein kinase C isoforms (IC50 = 50 µM). Also inhibits cyclic-nucleotide-dependent protein kinases.
Catalogue Number371956
Brand Family Calbiochem®
Synonyms1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl
References
ReferencesQuick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657.
Product Information
CAS number140663-38-3
FormFaint yellow lyophilized solid
Hill FormulaC₁₄H₁₇N₃O₂S · 2HCl
Chemical formulaC₁₄H₁₇N₃O₂S · 2HCl
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetPKC isoforms
Primary Target IC<sub>50</sub>50 µM
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
371956 0

Documentation

References

Hivatkozások áttekintése
Quick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision25-June-2008 JSW
Synonyms1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, 2HCl
DescriptionCell-permeable and less potent than H-7 in inhibiting rat brain protein kinase C isoforms (IC50 = 50 µM). Also inhibits other cyclic-nucleotide-dependent protein kinases.
FormFaint yellow lyophilized solid
Intert gas (Yes/No) Packaged under inert gas
CAS number140663-38-3
Chemical formulaC₁₄H₁₇N₃O₂S · 2HCl
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (1 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 6 months at 4°C.
Toxicity Standard Handling
ReferencesQuick, J., et al. 1992. Biochem. Biophys. Res. Commun. 187, 657.