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407252 Insulin-Like Growth Factor-I, Mouse, Recombinant, E. coli

407252
  
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Áttekintés

Kulcsspecifikációk táblázata

Purity
≥98% by SDS and HPLC
Description
Overview

This product has been discontinued.



Full-length, recombinant, mouse insulin-like growth factor I (IGF-I) expressed in E. coli. IGF-I regulates proliferation and survival signals through the Akt pathway. Mouse IGF-I shares 94% sequence identity with human IGF-I and exhibits cross-species reactivity. Useful in the study of cell proliferation and survival signals.

Catalogue Number407252
Brand Family Calbiochem®
SynonymsmIGF-I
References
ReferencesClemmons, D.R., et al. 2006. Curr. Opin. in Pharmacol. 6, 620.
Bell, G.I., et al. 1986. Nucleic Acids Res. 14, 7873.
Product Information
FormLyophilized
FormulationSterile-filtered prior to lyophilization. Contains no additives.
Quality LevelMQ100
Biological Information
Biological activityED₅₀: ≤2 ng/ml (corresponding to a specific activity of ≥1 x 10⁶ units/mg) as determined by a cell proliferation assay using FDC-P1 cells. For most in vitro applications IGF-I exerts is biological activity in the concentration range of 1-20 ng/ml.
Purity≥98% by SDS and HPLC
Physicochemical Information
ContaminantsEndotoxin: ≤1 ng/µg IGF-I
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions. Aliquots may be stored at 4°C for up to 1 week without loss of biological activity.
Global Trade Item Number
Katalógusszám GTIN
407252 0