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475995 InhibitorSelect™ mTOR Signaling Regulators Panel - Calbiochem

475995
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Overview

This product has been discontinued.



A panel containing 17 potent and selective small molecule regulators that is useful for the study of mTOR signaling: 1 mg of Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (Cat. No. 124018), 10 mg of Akt Inhibitor XVI, AT7867 (Cat. No. 124033), 1 mg of AMPK Inhibitor, Compound C (Cat. No. 171260), 10 mg of bpV(phen) (Cat. No. 203695), 5 mg of Compound 401 (Cat. No. 234501), 1 mg of H-89, Dihydrochloride (Cat. No. 371963), 5 mg of mTOR Inhibitor III, PP242 (Cat. No. 475988), 5 mg of mTOR Inhibitor IV, Ku-63794 (Cat. No. 475990), 5 mg of PDK1 Inhibitor II, BX-517 (Cat. No. 521276), 1 mg of PI-103 (Cat. No. 528100), 1 mg of PI 3-Kβ Inhibitor VI, TGX-221 (Cat. No. 528113), 5 mg of PTK/PI 3-K/mTOR Inhibitor, PP121 (Cat. No. 529584), 1 mg of Rapamycin (Cat. No. 553210), 10 mg of S6K1 Inhibitor, PF-4708671 (Cat. No. 559273), 10 mg of SHIP1 Inhibitor, 3AC (Cat. No. 565835), 10 mg of SHIP2 Inhibitor, AS1938909 (Cat. No. 565840), 1 mg of U0126 (Cat. No. 662005). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.

Catalogue Number475995
Brand Family Calbiochem®
References
ReferencesZoncu, R., et al. 2011. Nat. Rev. Mol. Cell Biol. 12, 21.
Foster, K.G. and Fingar, D.C., 2010. J. Biol. Chem. 285, 14071.
Albert, S., et al. 2010. Expert Opin. Investing Drugs 19, 919.
Hoeffer, C.A. and Klann, E., 2010. Trends Neurosci. 33, 67.
Laplante, M. and Sabatini, D.M., 2009. J. Cell Sci. 122, 3589.
Meric-Bernstam, F. and Gonzalez-Angulo, A.M., 2009. J. Clin. Oncol. 27, 2278.
Faivre, S., et al. 2006. Nat. Rev. Drug Discov. 5, 671.
Product Information
FormSolid
Quality LevelMQ100
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
475995 0

Documentation

InhibitorSelect™ mTOR Signaling Regulators Panel - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Hivatkozások áttekintése
Zoncu, R., et al. 2011. Nat. Rev. Mol. Cell Biol. 12, 21.
Foster, K.G. and Fingar, D.C., 2010. J. Biol. Chem. 285, 14071.
Albert, S., et al. 2010. Expert Opin. Investing Drugs 19, 919.
Hoeffer, C.A. and Klann, E., 2010. Trends Neurosci. 33, 67.
Laplante, M. and Sabatini, D.M., 2009. J. Cell Sci. 122, 3589.
Meric-Bernstam, F. and Gonzalez-Angulo, A.M., 2009. J. Clin. Oncol. 27, 2278.
Faivre, S., et al. 2006. Nat. Rev. Drug Discov. 5, 671.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-June-2013 JSW
DescriptionA panel containing 17 potent and selective small molecule regulators that is useful for the study of mTOR signaling. This panel contains the following inhibitors as well as 15 ml anhydrous DMSO for reconstitution:
FormSolid
Intert gas (Yes/No) Packaged under inert gas
SolubilityDMSO (supplied). Please refer to information provided on the CD for reconstitution information of individual inhibitors.
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesZoncu, R., et al. 2011. Nat. Rev. Mol. Cell Biol. 12, 21.
Foster, K.G. and Fingar, D.C., 2010. J. Biol. Chem. 285, 14071.
Albert, S., et al. 2010. Expert Opin. Investing Drugs 19, 919.
Hoeffer, C.A. and Klann, E., 2010. Trends Neurosci. 33, 67.
Laplante, M. and Sabatini, D.M., 2009. J. Cell Sci. 122, 3589.
Meric-Bernstam, F. and Gonzalez-Angulo, A.M., 2009. J. Clin. Oncol. 27, 2278.
Faivre, S., et al. 2006. Nat. Rev. Drug Discov. 5, 671.