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539745 InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II - Calbiochem

539745
  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
OverviewThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II consists of 80, well-characterized, cell permeable, potent and reversible protein kinase inhibitors; the majority of which are ATP-competitive. They are supplied in a convenient 96-well plate format at a concentration of 10 mM in DMSO. The inhibitors in this library will be useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications.
Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.

Download a list of all inhibitors of library II, including a comprehensive data set.
Catalogue Number539745
Brand Family Calbiochem®
Application Data

** Total higher than 80, as some inhibitors target kinases in other branches as well CMGC: Cdk, MAP, GSK3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases AGC: PKA, PKG, and PKC Containing Group CK: Casein Protein Kinases TK: Tyrosine Kinase Group STE: Yeast Sterile Protein Kinases
References
Product Information
Form96-well plate
FormulationAll of the inhibitors are supplied at a concentration of 10 mM in DMSO (50 µl/well).
Hygroscopic Hygroscopic
Applications
ApplicationThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II consists of 80, well-characterized, cell permeable, potent and reversible protein kinase inhibitors.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Irritant
Storage ≤ -70°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
539745 0

Documentation

InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II - Calbiochem Certificates of Analysis

TitleLot Number
539745

Data Sheet

Title
Reprogramming Cell Fate and Function Novel Strategies for iPSC Generation, Characterization, and Differentiation

Citations

Titulus
  • Hou, P., et al. 2013. Science 341, 651.
  • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
  • Yinghong Gao, et al. 2013. Biochem. J. in press.
  • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
  • Cohen, T., et al. 2012. Biochem. J. in press.
  • Elkaim, J., 2012. Biochem. J. in press.
  • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
  • Lee, A.J., et al. 2011. Cancer Res. 71, 1858.
  • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
  • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
  • Donovi, D., et al. 2010 Biochem Soc Trans. 38, 1067.
  • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
  • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 10.1021/ja910361r
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision11-September-2012 JSW
    Application Data

    ** Total higher than 80, as some inhibitors target kinases in other branches as well CMGC: Cdk, MAP, GSK3, and CLK Containing Group CAMK: Ca2+/Calmodulin Dependent Protein Kinases AGC: PKA, PKG, and PKC Containing Group CK: Casein Protein Kinases TK: Tyrosine Kinase Group STE: Yeast Sterile Protein Kinases
    DescriptionThe InhibitorSelect™ 96-Well Protein Kinase Inhibitor Library II consists of 80, well-characterized protein kinase inhibitors, the majority of which are cell-permeable and ATP-competitive. The library is useful for target identification in drug discovery, biochemical pathway analysis, screening new protein kinases, and other pharmaceutical-related applications. Supplied with a CD containing comprehensive documentation for each inhibitor. Please contact technical service for further details.
    Form96-well plate
    FormulationAll of the inhibitors are supplied at a concentration of 10 mM in DMSO (50 µl/well).
    Intert gas (Yes/No) Packaged under inert gas
    Storage Protect from light
    ≤ -70°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsThe contents of this pouch have been purged under nitrogen and are vacuum sealed. Cut open the pouch, take the plate out of the pouch, and let it thaw at room temperature. Please remove the lid gently. To re-store, purge with an inert gas, replace the lid tightly, place in a sealable bag, and store at -70°C in an upright position. Minimize freeze/thaw cycles. This product is stable for one year after receipt.
    Toxicity Irritant
    Citation
  • Hou, P., et al. 2013. Science 341, 651.
  • Ali, H.A., et al. 2013. ACS Chem. Biol. in press.
  • Yinghong Gao, et al. 2013. Biochem. J. in press.
  • Zhonghan Li1 and Tariq M. Ranal. 2012. Nature Comm. 3, 1085.
  • Cohen, T., et al. 2012. Biochem. J. in press.
  • Elkaim, J., 2012. Biochem. J. in press.
  • Baxter, B.K., et al. 2011. ACS Chem. Biol. in press.
  • Lee, A.J., et al. 2011. Cancer Res. 71, 1858.
  • Wong, S.W., et al. 2010. Breast Cancer Res. Treat. in press.
  • Chou, T-F. and Deshaies, R.J., 2011. JBC Papers in Press.
  • Donovi, D., et al. 2010 Biochem Soc Trans. 38, 1067.
  • Hooper, S., et al. 2010. British Journal of Cancer 102, 392.
  • Gronenberg, L.S., and Kahne, d., 2009. J. Am. Chem. Soc. 10.1021/ja910361r