Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

371545 Guanosine 5ʹ-O-(3-Thiotriphosphate), Tetralithium Salt - CAS 94825-44-2 - Calbiochem

371545
  
Purchase on Sigma-Aldrich

Áttekintés

Kulcsspecifikációk táblázata

CAS #Empirical Formula
94825-44-2C₁₀H₁₂N₅O₁₃P₃S . 4Li
Description
OverviewG-protein-activating GTP analog, which is more resistant to hydrolysis than GTP. Induces exocytosis in isolated mouse pancreatic acinar cells. Also reported to stimulate insulin release from pancreatic β-cells.
Catalogue Number371545
Brand Family Calbiochem®
SynonymsGTPγ-S, 4Li
References
ReferencesIino, S., et al. 2000. FEBS Lett. 479, 46.
Martelli, A.M., et al. 1996. Biochem. Biophys. Res. Commun. 218, 182.
Hess, S.D., et al. 1993. Science 259, 1169.
Ekstrom, R.C., et al. 1992. J. Biol. Chem. 267, 22183.
McGuirk, S.M., and Dolphin, A.C. 1992. Neurosci. 49, 117.
Vaca, L., et al. 1992. Eur. J. Physiol. 422, 66.
Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466.
Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
Orellana, S., et al. 1987. J. Biol. Chem.. 262, 1638.
Product Information
CAS number94825-44-2
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₀H₁₂N₅O₁₃P₃S . 4Li
Chemical formulaC₁₀H₁₂N₅O₁₃P₃S . 4Li
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetG-protein-activating GTP analog
Purity≥85% by HPLC.
Physicochemical Information
Cell permeableN
ContaminantsGDP: ≤12%
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions lose about 5% of their activity after 6 months at -20°C.
Global Trade Item Number
Katalógusszám GTIN
371545 0