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370677 Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem

370677
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Áttekintés

Kulcsspecifikációk táblázata

Empirical Formula
C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N

Products

KatalógusszámCsomagolás Menny./csomag
370677-1UMOL Muanyagampulla 1 umol
Description
OverviewA potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Significantly more lipophilic and membrane-permeable than Rp-cGMPS or Rp-8-Br-cGMPS (Cat. No. 370674). Note: 1 µmol = 0.61 mg.
Catalogue Number370677
Brand Family Calbiochem®
SynonymsRp-8-pCPT-cGMPS, TEA, PKG Inhibitor III
References
ReferencesAbd Alla, S., et al. 1996. Eur. J. Biochem. 241, 498.
Lee, S.J., et al. 1996. Dev. Biol. 180, 324.
Van Uffelen, B.E., et al. 1996. J. Leukoc. Biol. 60, 94.
Willmott, N., et al. 1996. J. Biol. Chem. 271, 3699.
Butt, E., et al. 1994. Eur. J. Pharmacol. 269, 265.
Product Information
ATP CompetitiveN
DeclarationSold under license of U.S. Patent 5,625,056, Patents DE 3,802,865.4, and DE 4,217,679 issued to BIOLOG LSI.
FormLyophilized
Hill FormulaC₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N
Chemical formulaC₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetPKG1α
Purity≥99% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Katalógusszám GTIN
370677-1UMOL 04055977191707