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505311 Gallamine Triethiodide - CAS 65-29-2 - Calbiochem

Gallamine Triethiodide - CAS 65-29-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide

Primary Target: mAChR
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
65-29-2C₃₀H₆₀I₃N₃O₃
Description
Overview

This product has been discontinued.



A negative allosteric modulator selective for muscarinic AChRs. Most selective for M2 receptors (Ki = 2.4 nM) over other mAChRs (M2 > M1 = M4 > M3 = M5). Used to study the roles of M2 receptors in neuromuscular transmission and neuroimmunology.
Catalogue Number505311
Brand Family Calbiochem®
Synonyms2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide
References
ReferencesBeltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
Burke, E., 1986. Mol. Pharmacol. 30, 58.
Product Information
CAS number65-29-2
FormWhite powder
Hill FormulaC₃₀H₆₀I₃N₃O₃
Chemical formulaC₃₀H₆₀I₃N₃O₃
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetmAChR
Primary Target K<sub>i</sub>2.4 nM
Purity≥98% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
505311 0

Documentation

Gallamine Triethiodide - CAS 65-29-2 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Hivatkozások áttekintése
Beltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
Burke, E., 1986. Mol. Pharmacol. 30, 58.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-July-2013 JSW
Synonyms2,2ʹ,2ʹʹ-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethanaminium) iodide, Muscarinic Receptor Antagonist, Gallamine Triethiodide, Muscarinic mAChR Antagonist, Gallamine Triethiodide
DescriptionA negative allosteric modulator selective for muscarinic AChRs. Most selective for M2 receptors (Ki = 2.4 nM) over other mAChRs (M2 > M1 = M4 > M3 = M5). Used to study the roles of M2 receptors in neuromuscular transmission and neuroimmunology.
FormWhite powder
CAS number65-29-2
Chemical formulaC₃₀H₆₀I₃N₃O₃
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (100 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesBeltrame, P., 2011. Clin. Exp. Immunol. 164, 170.
Gnagey, A., et al., 1999. Mol. Pharmacol. 56, 1245.
Leppik, A., et al. 1994. Mol. Pharmacol. 45, 983.
Burke, E., 1986. Mol. Pharmacol. 30, 58.