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344514 FTase Inhibitor III

FTase Inhibitor III MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: H-Cys-Val-2-Nal-Met-OH(Nal= 2-naphthylalanine)

Primary Target: FTase
344514
  
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Empirical Formula
C₂₆H₃₆N₄O₅S₂
Description
Overview

This product has been discontinued.





A potent synthetic inhibitor of p21ras farnesyltransferase (FTase; IC50 = 12 nM).
Catalogue Number344514
Brand Family Calbiochem®
SynonymsH-Cys-Val-2-Nal-Met-OH(Nal= 2-naphthylalanine)
References
ReferencesHamilton, A.D., and Sebti, S.M. 1995. Drug News Perspect. 8, 138.
Leftheris, K., et al. 1994. Bioorg. Med. Chem. Lett. 4, 887.
Product Information
FormWhite solid
Hill FormulaC₂₆H₃₆N₄O₅S₂
Chemical formulaC₂₆H₃₆N₄O₅S₂
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetFTase
Primary Target IC<sub>50</sub>12 nM
Purity≥95% by HPLC
Physicochemical Information
Peptide SequenceH-Cys-Val-2-Nal-Met-OH (Nal = naphthylalanine)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
344514 0

Documentation

FTase Inhibitor III Certificates of Analysis

TitleLot Number
344514

References

Hivatkozások áttekintése
Hamilton, A.D., and Sebti, S.M. 1995. Drug News Perspect. 8, 138.
Leftheris, K., et al. 1994. Bioorg. Med. Chem. Lett. 4, 887.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-June-2008 RFH
SynonymsH-Cys-Val-2-Nal-Met-OH(Nal= 2-naphthylalanine)
DescriptionMost potent synthetic inhibitor of p21ras farnesyltransferase (FTase; IC50 = 12 nM).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₂₆H₃₆N₄O₅S₂
Peptide SequenceH-Cys-Val-2-Nal-Met-OH (Nal = naphthylalanine)
Structure formulaStructure formula
Purity≥95% by HPLC
Solubility50% Acetic acid
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHamilton, A.D., and Sebti, S.M. 1995. Drug News Perspect. 8, 138.
Leftheris, K., et al. 1994. Bioorg. Med. Chem. Lett. 4, 887.