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509706 DFB - CAS 15332-10-2 - Calbiochem

A positive allosteric modulator for mGlu receptor subtype 5 (EC₅₀ = 2 - 5.3 µM).

DFB - CAS 15332-10-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: [(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde, 3,3ʹ-Difluorobenzaldazine

Primary Target: mGlu₅
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
15332-10-2C₁₄H₁₀F₂N₂
Description
Overview

This product has been discontinued.



A positive allosteric modulator for mGlu receptor subtype 5 (EC50 = 2 - 5.3 µM). No agonistic action on mGlu5. Renders 3-6 fold potentiation for Glu5 agonists. No effect on other mGlu receptor subtypes.

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number509706
Brand Family Calbiochem®
Synonyms[(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde, 3,3ʹ-Difluorobenzaldazine
References
ReferencesOʹBrien, J., et al. 2003. Mol. Pharmacol. 64, 731.
Zhang Z., et al. 2005. J. Pharmacol. Exp. Ther. 315, 1212.
Product Information
CAS number15332-10-2
FormYellow solid
Hill FormulaC₁₄H₁₀F₂N₂
Chemical formulaC₁₄H₁₀F₂N₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetmGlu₅
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
509706 0

Documentation

DFB - CAS 15332-10-2 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Hivatkozások áttekintése
OʹBrien, J., et al. 2003. Mol. Pharmacol. 64, 731.
Zhang Z., et al. 2005. J. Pharmacol. Exp. Ther. 315, 1212.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-February-2014 JSW
Synonyms[(3-Fluorophenyl)methylene]hydrazone-3-fluorobenzaldehyde, 3,3ʹ-Difluorobenzaldazine
DescriptionA positive allosteric modulator for mGlu receptor subtype 5 (EC50 = 2 - 5.3 µM). No agonistic action on mGlu5. Renders 3-6 fold potentiation for Glu5 agonists. No effect on other mGlu receptor subtypes.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number15332-10-2
Chemical formulaC₁₄H₁₀F₂N₂
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (12 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesOʹBrien, J., et al. 2003. Mol. Pharmacol. 64, 731.
Zhang Z., et al. 2005. J. Pharmacol. Exp. Ther. 315, 1212.