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230752 Chromomycin A₃ - CAS 7059-24-7 - Calbiochem

Antitumor antibiotic that inhibits RNA synthesis. A cell-permeable fluorescent dye that can be used with Bisbenzimide H 33258 to distinguish chromosomes by their total DNA content and DNA base composition.

Chromomycin A₃ - CAS 7059-24-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Toyomycin

230752
  
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
7059-24-7C₅₇H₈₂O₂₆
Description
OverviewAntitumor antibiotic that inhibits RNA synthesis. A cell-permeable fluorescent dye that can be used with Bisbenzimide H 33258 (Cat. No. 382061) to distinguish chromosomes by their total DNA content and DNA base composition. Reversibly interacts with DNA in the presence of Mg2+. Binds to G:C pairs of helical DNA but does not intercalate.
Catalogue Number230752
Brand Family Calbiochem®
SynonymsToyomycin
References
ReferencesAich, P., et al. 1992. Biochemistry 31, 2988.
Saccone, S., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 4913.
Van Dilla, M.A., et al. 1983. Science 220, 620.
Mizuno, K. 1963. J. Antibiot. 16, 22.
Product Information
CAS number7059-24-7
FormYellow solid
Hill FormulaC₅₇H₈₂O₂₆
Chemical formulaC₅₇H₈₂O₂₆
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥90% by HPLC
Physicochemical Information
Emission max.
Excitation max.
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGB7875000
Safety Information
R PhraseR: 26/27/28-61

Very toxic by inhalation, in contact with skin and if swallowed.
May cause harm to the unborn child.
S PhraseS: 26-36/37/39-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Highly Toxic & Carcinogenic / Teratogenic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing recosntitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
230752 0

Documentation

Chromomycin A₃ - CAS 7059-24-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Chromomycin A₃ - CAS 7059-24-7 - Calbiochem Certificates of Analysis

TitleLot Number
230752

References

Hivatkozások áttekintése
Aich, P., et al. 1992. Biochemistry 31, 2988.
Saccone, S., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 4913.
Van Dilla, M.A., et al. 1983. Science 220, 620.
Mizuno, K. 1963. J. Antibiot. 16, 22.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision29-April-2008 RFH
SynonymsToyomycin
DescriptionAntibiotic that inhibits RNA synthesis by way of DNA-dependent RNA polymerase. Fluorescent dye that can be used in conjunction with Bisbenzimide H33258 (Cat. No. 382061) to distinguish chromosomes by their total DNA concentration and their DNA base composition. Binds to G:C pairs of helical DNA (Mg2+ required) but does not intercalate the A:T pairs, which preferentially bind Bisbenzimide H33258.
FormYellow solid
CAS number7059-24-7
RTECSGB7875000
Chemical formulaC₅₇H₈₂O₂₆
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityEthanol (10 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing recosntitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Highly Toxic & Carcinogenic / Teratogenic
Merck USA index14, 2238
ReferencesAich, P., et al. 1992. Biochemistry 31, 2988.
Saccone, S., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 4913.
Van Dilla, M.A., et al. 1983. Science 220, 620.
Mizuno, K. 1963. J. Antibiot. 16, 22.