C101256Millipore offers a significant portfolio of well-published, quantitative and optimized live cell, whole-cell, and cell-based activity assays. Study Apoptosis, Angiogensis, Adhesion and more.
EMD Millipore offers a significant portfolio of well-published, quantitative and optimized live cell, whole-cell and cell-based activity assays that mimic native environments for direct and indirect detection of cellular response. These techniques facilitate protein target validation, identify cellular events, interrogate intracellular pathways and determine the mechanisms of cellular action under user-defined conditions.
EMD Millipore’s cell-based assays can be used to visualize and characterize cellular mechanisms, measure cell-specific biochemical effects, and help identify targets as potential therapeutic candidates.
Apoptosis/Cell Death
The ability to elude programmed cell death (apoptosis) is a hallmark of most types of cancer. EMD Millipore’s cell-based assays for apoptosis include our best-selling and well-published ApopTag® family of In Vivo TUNEL assays and CaspaTag™ family of In Situ Caspase detection assays to help researchers interrogate the fine balance between cell survival and death.
Click on the Ordering tab to see our Apoptosis/Cell Death cell-based assays.
Cell Migration/Invasion
Metastasis is the cumulative result of multiple changes in tumor cells and their
microenvironment that enable cells to migrate or invade into healthy host tissue. EMD Millipore’s vast portfolio of migration, invasion, chemotactic and haptotactic Boyden Chamber assays enable researchers to simulate the barriers invaded by and conditions encountered by metastatic tumor cells in vivo.
Click on the Ordering tab to see our Cell Migration/Invasion cell-based assays.
Angiogenesis & Endothelial Transmigration
The development of new vascular networks (angiogenesis) is a necessary component of tumor growth and metastasis. Of similar importance, the ability of immune cells to migrate through newly formed vasculature is a key component of the host’s immune response to cancer. EMD Millipore provides various cell-based assays to both interrogate endothelial tube formation and evaluate the effects of chemicals and drugs on endothelial monolayer adsorption, transport, and permeability.
Click on the Ordering tab to see our Angiogenesis & Endothelial transmigration cell-based assays.
Cell Adhesion
The mechanism by which cells bind to one another and to the extracellular matrix (ECM) is regulated by a large family of transmembrane receptors. Cell adhesion plays a critical role in cell growth, differentiation, survival, motility, as well as a necessary component of tumor metastasis. EMD Millipore provides a family of whole cell adhesion arrays to help interrogate the roles that integrins and ECM proteins play in normal and abnormal cell adhesion.
Click on the Ordering tab to see our Cell Adhesion cell-based assays.
Cell Growth & Transformation
Cellular growth, transformation, proliferation and differentiation are important cellular activities under normal and abnormal conditions. EMD Millipore provides various cell-based assays designed to interrogate cellular senescence due to aging, cellular transformation due to genetic mutations, and specific cellular differentiation related to skeletal myogenesis.
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