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203292 Bisindolylmaleimide II - CAS 137592-45-1 - Calbiochem

203292
  
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Áttekintés

Kulcsspecifikációk táblázata

CAS #Empirical Formula
137592-45-1C₂₇H₂₆N₄O₂
Description
Overview

This product has been discontinued.



A potent, cell permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC50 = 13 nM). May inhibit protein kinase A at much higher concentrations (IC50 = 2 µM).

Catalogue Number203292
Brand Family Calbiochem®
Synonyms2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide
References
ReferencesToullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
Product Information
CAS number137592-45-1
ATP CompetitiveY
FormOrange solid
Hill FormulaC₂₇H₂₆N₄O₂
Chemical formulaC₂₇H₂₆N₄O₂
ReversibleY
Structure formula ImageStructure formula Image
Biological Information
Primary TargetPKC
Primary Target IC<sub>50</sub>13 nM against protein kinase C
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Global Trade Item Number
Katalógusszám GTIN
203292 0