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14-521 Arg Protein, active, human, 10 µg

Active, human, N-terminal His6-tagged recombinant human Arg, residues 38-end. For use in Kinase Assays.

Arg Protein, active, human, 10 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-521
10 µg  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information
Description
Catalogue Number14-521
Brand Family Upstate
Trade Name
  • Upstate
DescriptionArg Protein, active, human, 10 µg
OverviewN-terminal His6-tagged recombinant human Arg, residues 38-end.
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, human, N-terminal His6-tagged recombinant human Arg, residues 38-end. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceHuman Arg expressed by baculovirus in Sf21 insect cells.
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryThe gene product is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. This gene is expressed in both normal and tumor cells. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Gene Symbol
  • ABL2
  • Abelson-related
  • ABLL
  • ARG
Protein TargetArg
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
COFACTOR: Magnesium or manganese.
SIZE: 1182 amino acids; 128343 Da
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Widely expressed.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Molecular Weight121.9 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of Abltide.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
14-521 04053252619052