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MABN503 Anti-WAVE-1 Antibody, clone K91/36

MABN503
100 µg  
Purchase on Sigma-Aldrich

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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, H, MWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN503
DescriptionAnti-WAVE-1 Antibody, clone K91/36
Alternate Names
  • Wiskott-Aldrich syndrome protein family member 1
  • WASP family protein member 1
  • Protein WAVE-1
  • Verprolin homology domain-containing protein 1
Background InformationProtein WAVE-1 (WAVE1) is also known as Wiskott-Aldrich syndrome protein (WASP) family member 1 (WASF1), verprolin homology domain-containing protein 1, or SCAR1. WAVE1 is a downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. WAVE1 binds actin and ARP2/3 complex. It binds the ARP2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain. WAVE1 is highly expressed in brain, with low expression in several other tissue.
References
Product Information
FormatPurified
Control
  • Rat brain tissue lysate
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect WAVE1 using this mouse monoclonal antibody, Anti-WAVE-1 Antibody, clone K91/36 validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A representative lot detected WAVE-1 in adult rat hippocampal CA1 tissue (Prof. J. Trimmer, University of California, Davis).
Biological Information
ImmunogenLinear peptide corresponding to human WAVE-1.
CloneK91/36
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Rat
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • WASF1
  • KIAA0269
  • SCAR1
  • WAVE1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 70 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected WAVE-1 in 10 µg of rat brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABN503 04053252906442