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AB5573-200UL Anti-Urotensin II Receptor Antibody

AB5573-200UL
200 µL  
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Replacement Information

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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB5573-200UL
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Urotensin II Receptor Antibody
Alternate Names
  • UTIIR
  • UR2R
  • G Protein Coupled Receptor 14
References
Product Information
FormatAffinity Purified
Control
  • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
PresentationAffinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA, 5% sucrose and 0.05% sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).
Quality LevelMQ100
Applications
ApplicationAnti-Urotensin II Receptor Antibody detects level of Urotensin II Receptor & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern blotting: 1:200 using ECL on rat kidney membranes.Dilutions should be made using a carrier protein such as BSA (1-3%). See protocol.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenHighly purified peptide corresponding to residues 154-167 of rat UTIIR (Accession P49684).
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes Urotensin II Receptor (UTIIR, UR2U). The epitope specific for Urotensin II Receptor is not present in any other known proteins.

The immunogen sequence is identical in bovine and conserved in canine (13/14) and human (13/14). Reactivity with other species has not yet been tested.
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • UTS2R
  • UR-II-R
  • UTR
  • UTR2
  • GPR14
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9UKP6 # High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
SIZE: 389 amino acids; 42130 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Most abundant expression in the heart and pancreas.
SIMILARITY: SwissProt: Q9UKP6 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20°C for up to 6 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
AB5573-200UL 04053252274534