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ABN1014 Anti-UFD1L Antibody

ABN1014
100 µg  
Purchase on Sigma-Aldrich

Különleges ajánlatok

Áttekintés

Replacement Information

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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN1014
DescriptionAnti-UFD1L Antibody
Alternate Names
  • UFD1L
  • Ubiquitin fusion degradation protein 1 homolog
  • UB fusion protein 1
Background InformationUFD1L is an essential component of the ubiquitin dependent proteolytic pathway which degrades ubiquitin fusion proteins. UFD1L is part of the three protein complex of UFD1L, VCP and NPLOC4 that binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the proteasome. The complex also regulates spindle disassembly during mitosis and plays an important role in ectoderm development as well. In the adult UFD1L is widely expressed but highest levels are in heart, skeletal muscle, and pancreas.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-UFD1L Antibody is an antibody against UFD1L for use in Immunohistochemistry and Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected UFD1L in human pancreas tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human UFD1L.
EpitopeUnknown
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Bat, Monkey, Primate, Baboon based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • UFD1L
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~38 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human skeletal muscle tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected UFD1L in 10 µg of human skeletal muscle tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
ABN1014 04055977135251