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MABT75 Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1

Anti-Titin (N-terminal/Z-domain) Antibody, clone 17D11.1 is an antibody against Titin (N-terminal/Z-domain) for use in Western Blotting, IHC(P).

Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeleton Gene Symbol: TTN UniProt Number: Q8WZ42
MABT75
100 µg  
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Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT75
DescriptionAnti-Titin (NT/Z-domain) Antibody, clone 17D11.1
Alternate Names
  • Titin
  • Connectin
  • Rhabdomyosarcoma antigen MU-RMS-40.14
Background InformationTitin is a large complex protein containing over one hundred IgG-like and fibronectin type-III domains, in addition to multiple Kelch, RCC1, TPR, and WD repeats. It is a member of the CAMK Ser/Thr protein kinase family and also possesses a protein kinase domain, which is involved in controlling gene expression and protein turnover in muscle tissues. Titin also functions as a sensor to mediate appropriate cellular responses to mechanical stress. In striated muscle tissue, titin regulates the length of the sarcomere by integrating myosin and actin filaments at the Z-disk and M-band, and facilitates the elasticity of the sarcomere. Titin also regulates sarcomere assembly and functions as central hub in signal transduction pathways. Defects in Titin may contribute to various forms of cardiomyopathy.
References
Product Information
FormatPurified
Control
  • Human and mouse cardiac muscle tissues
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Titin (N-terminal/Z-domain) Antibody, clone 17D11.1 is an antibody against Titin (N-terminal/Z-domain) for use in Western Blotting, IHC(P).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Titin.
Clone17D11.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TTN
Purification MethodProtein G Purified
UniProt Number
Molecular Weight38 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in human and mouse cardiac muscle tissues.

Immunohistochemistry Analysis: 1:1,000 dilution of this antibody detected Titin in human and mouse cardiac muscle tissues.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABT75 04053252646331

Documentation

Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Titin (NT/Z-domain) Antibody, clone 17D11.1 Certificates of Analysis

TitleLot Number
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 2433594 2433594
Anti-Titin (N-terminal/Z-domain), -2724172 2724172
Anti-Titin (N-terminal/Z-domain), -2774076 2774076
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3311782 3311782
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3386473 3386473
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3736709 3736709
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3880435 3880435
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - 3899582 3899582
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 - Q2015738 Q2015738
Anti-Titin (N-terminal/Z-domain), clone 17D11.1 Monoclonal Antibody 3134088
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Brochure

Title
New Products: Volume 3, 2012