Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

MABF1961 Anti-Thy 1.1 (CD90) Antibody, clone T11D7e

This mouse monoclonal Anti-Thy 1.1 (CD90), clone T11D7e, Cat. No. MABF1961 is validated for use in Flow Cytometry for the detection of Thy-1 membrane glycoprotein, CD90.

Anti-Thy 1.1 (CD90) Antibody, clone T11D7e MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Gene Symbol: Thy1, Thy-1 UniProt Number: P01830
MABF1961
200 µL  
Purchase on Sigma-Aldrich

Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, MFCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABF1961
DescriptionAnti-Thy 1.1 (CD90) Antibody, clone T11D7e
Alternate Names
  • Thy-1 membrane glycoprotein
  • Thy-1 antigen
  • CD90
Background InformationThy-1 membrane glycoprotein (UniProt: P01830; also known as Thy-1 antigen, CD90) is encoded by the Thy1 (also known as Thy-1) gene (Gene ID: 24832) in rat. Thy-1 is a heavily glycosylated, GPI-anchored membrane glycoprotein that is distributed throughout mammalian species. Thy-1 is synthesized with a 19 amino acid signal sequence and 31 amino acid C-terminal transmembrane domain that is present in pro form, but removed when transferring the 112 amino acid mature peptide to GPI anchor. It is present in large amounts on thymus and brain cells and in smaller quantities on fibroblasts, epidermal cells, mammary glands and immature skeletal muscle. In many of these tissues the level of Thy-1 expression changes dramatically during cell differentiation. Thy-1 plays a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Thy-1 is one of the most heavily glycosylated membrane proteins with a carbohydrate content up to 30% of its molecular mass. In most species Thy-1 has 3 N-glycosylation sites (Asn 23, 74, and 98) but no O-glycosylation. The glycosylation appears to be tissue specific and the composition of Thy-1 carbohydrate moieties is shown to vary between different tissues or even among cells of the same lineage at different stages of differentiation. Thy-1 is a differentiation marker for thymocytes and can serve as a surrogate marker for various kinds of stem cells.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal antibody IgM in PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis mouse monoclonal Anti-Thy 1.1 (CD90), clone T11D7e, Cat. No. MABF1961 is validated for use in Flow Cytometry for the detection of Thy-1 membrane glycoprotein, CD90.
Key Applications
  • Flow Cytometry
Application NotesFlow Cytometry Analysis: A representative lot detected Thy 1.1 (CD90) in CAK1.3 and CAK4.4 cell lines (Ogasawara, K., et. al. (1990). Microbiol. Immunol. 34(12):1025-39).
Biological Information
ImmunogenXenogenic rat thymocytes.
Epitopeextracellular domain
CloneT11D7e
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityClone T11D7e detects Thy-1.1 (CD90) in rat thymocytes.
IsotypeIgMκ
Species Reactivity
  • Rat
  • Mouse
Species Reactivity NoteRat, Mouse.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Thy1
  • Thy-1
UniProt Number
Molecular Weight18.17 kDa calulated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Flow Cytometry in rat thymocytes.

Flow Cytometry Analysis: 1 µg of this antibody detected Thy 1.1 (CD90) in one million rat thymocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABF1961 04054839168703