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MABC98 Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1

MABC98
100 µg  
Purchase on Sigma-Aldrich

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Kulcsspecifikációk táblázata

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC98
DescriptionAnti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1
Alternate Names
  • Sphingosine 1-phosphate receptor 5
  • S1P receptor 5
  • S1P5
  • Endothelial differentiation G-protein-coupled receptor 8
  • Sphingosine 1-phosphate receptor Edg-8
  • S1P receptor Edg-8
Background InformationSphingosine 1-phosphate receptor 5 (S1PR5 or S1P5), otherwise known as EDG8, is a G-protein coupled receptor which is activated by the lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi/0 alpha and G12 signaling pathways. S1P5 is highly abundant in the brain, particularly in the corpus callosum, but S1P5 has also been detected in the spleen, placenta, lung, aorta, and peripheral blood leukocytes. In the brain, it regulates the transformation of radial glial cells into astrocytes, and the migration of oligodendrocyte precursor cells during development.
References
Product Information
FormatPurified
Control
  • Daudi cell lysate
PresentationPurified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Sphingosine 1-phosphate receptor 5 (S1P5) using this Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 validated for use in Western Blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 5 in normal human cerebellum and normal placenta tissue.
Biological Information
ImmunogenRecombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 5 (S1P5).
Clone13F9.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse based on immunogen design.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • S1PR5
  • EDG8
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~42 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in Daudi cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Sphingosine 1-phosphate receptor 5 in 10 µg of Daudi cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Katalógusszám GTIN
MABC98 04053252694257

Documentation

Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 Certificates of Analysis

TitleLot Number
Anti-Sphingosine 1-phosphate -2753831 2753831
Anti-Sphingosine 1-phosphate -2821239 2821239
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 3082668
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 2467146 2467146
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3228349 3228349
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3259078 3259078
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3439728 3439728
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - 3991484 3991484
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 - Q2037261 Q2037261
Anti-Sphingosine 1-phosphate receptor 5 (S1P5), clone 13F9.1 -2521710 2521710